Recent discoveries and applications involving small-molecule microarrays

•We review selected recent probe discoveries and novel applications using SMMs.•SMM screening can use purified protein and proteins from cellular lysates.•Both strategies have yielded effective probes and inhibitors for a wide variety of targets.•SMMs enable functional proteomics-biomarker discovery...

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Veröffentlicht in:	Current opinion in chemical biology 2014-02, Vol.18, p.21-28
Hauptverfasser:	Hong, Jiyoung A, Neel, Dylan V, Wassaf, Dina, Caballero, Francisco, Koehler, Angela N
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomarkers - metabolism Cell Survival Humans Microarray Analysis - methods Protein Binding Proteins - chemistry Proteins - metabolism Small Molecule Libraries - analysis Small Molecule Libraries - metabolism
Online-Zugang:	Volltext
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