Role of Insulin Resistance in the Pathogenesis and Development of Type 2 Diabetes in WBN/Kob-Leprfa Rats

WBN/Kob-Leprfa (fa/fa) rats have been identified as a new animal model of type 2 diabetes (T2DM), as they are characterized by impaired pancreatic insulin secretion and severe insulin resistance. Our previous study demonstrated impaired insulin secretion and its involvement in hyperglycemia in fa/fa...

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Veröffentlicht in:	Journal of Veterinary Medical Science 2013, Vol.75(12), pp.1557-1561
Hauptverfasser:	OKUNO, Akira, KAJI, Noriyuki, TAKAHASHI, Atsushi, NAGAKUBO, Dai, OHNO-ICHIKI, Kanako, SHIRAI, Mitsuyuki, ASAI, Fumitoshi
Format:	Artikel
Sprache:	eng
Schlagworte:	insulin resistance Pharmacology troglitazone type 2 diabetes WBN/Kob-Leprfa rat
Online-Zugang:	Volltext
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