Expression of the Matrix Metalloproteases 2, 14, 24, and 25 and Tissue Inhibitor 3 as Potential Molecular Markers in Advanced Human Gastric Cancer

Background. During progression of gastric cancer (GC), degradation of the extracellular matrix is mediated by the matrix metalloproteases (MMPs) and their tissue inhibitors (TIMPs): changes in the expression of these have been related to unfavorable prognosis in GC. Objective. To analyze the express...

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Veröffentlicht in:	Disease markers 2014-01, Vol.2014 (2014), p.1-9
Hauptverfasser:	León-Córdoba, Kenneth, Sampieri, Clara Luz, Ochoa-Lara, Mariana, Remes-Troche, José María, de la Peña, Sol
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Biological markers Biomarkers, Tumor - genetics Biomarkers, Tumor - metabolism Case-Control Studies Diagnosis Enzyme inhibitors Female Gastritis - metabolism Gene Expression Genetic aspects Health aspects Humans Identification and classification Male Matrix Metalloproteinases - genetics Matrix Metalloproteinases - metabolism Metalloproteins Middle Aged Prognosis Stomach cancer Stomach Neoplasms - enzymology Stomach Neoplasms - pathology Tissue Inhibitor of Metalloproteinase-3 - genetics Tissue Inhibitor of Metalloproteinase-3 - metabolism Transcriptome Young Adult
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