Reduced Expression of DNA Damage Repair Genes High Mobility Group Box1 and Poly(ADP-ribose) Polymerase1 in Inactive Carriers of Hepatitis B Virus Infection-A Possible Stage of Viral Integration

Background High mobility group box1 (HMGB1) and poly(ADP-ribose) polymerase1 (PARP1) proteins repair cellular DNA damage. Reduced expression of the corresponding genes can lead to an impaired DNA damage repair mechanism. Intracellular replication of hepatitis B virus (HBV) in such conditions can fav...

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Veröffentlicht in:	Journal of clinical and experimental hepatology 2013-06, Vol.3 (2), p.89-95
Hauptverfasser:	Mukherjee, Rathindra M, Shravanti, Gelli V, Jakkampudi, Aparna, Kota, Ramya, Jangala, Asha L, Reddy, Panyala B, Rao, Padaki N, Gupta, Rajesh, Reddy, Duvvuru N
Format:	Artikel
Sprache:	eng
Schlagworte:	Endocrinology & Metabolism Gastroenterology and Hepatology gene expression hepatitis B virus high mobility group box1 Original poly(ADP-ribose) polymerase1 pregenomic RNA
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