Long-Term Characterization of Axon Regeneration and Matrix Changes Using Multiple Channel Bridges for Spinal Cord Regeneration

Spinal cord injury (SCI) results in loss of sensory and motor function below the level of injury and has limited available therapies. The host response to SCI is typified by limited endogenous repair, and biomaterial bridges offer the potential to alter the microenvironment to promote regeneration....

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Veröffentlicht in:	Tissue engineering. Part A 2014-03, Vol.20 (5-6), p.127-1037
Hauptverfasser:	Tuinstra, Hannah M., Margul, Daniel J., Goodman, Ashley G., Boehler, Ryan M., Holland, Samantha J., Zelivyanskaya, Marina L., Cummings, Brian J., Anderson, Aileen J., Shea, Lonnie D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylcholinesterase - metabolism Animals Axons - pathology Calcitonin Gene-Related Peptide - metabolism Chondroitin Sulfates - metabolism Collagen Type I - metabolism Collagen Type IV - metabolism Extracellular Matrix - metabolism Female Fibronectins - metabolism Laminin - metabolism Matrix Myelin Sheath - metabolism Neurons Original Original Articles Rats Rats, Long-Evans Spinal cord Spinal Cord Injuries - enzymology Spinal Cord Injuries - pathology Spinal Cord Injuries - physiopathology Spinal Cord Injuries - therapy Spinal Cord Regeneration Time Factors Tissue engineering
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