Spatio-temporal requirements for transposable element piRNA-mediated silencing during Drosophila oogenesis

During Drosophila oogenesis, transposable element (TE) repression involves the Piwi-interacting RNA (piRNA) pathway which ensures genome integrity for the next generation. We developed a transgenic model to study repression of the Idefix retrotransposon in the germline. Using a candidate gene KD-app...

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Veröffentlicht in:	Nucleic acids research 2014-02, Vol.42 (4), p.2512-2524
Hauptverfasser:	Dufourt, Jérémy, Dennis, Cynthia, Boivin, Antoine, Gueguen, Nathalie, Théron, Emmanuelle, Goriaux, Coline, Pouchin, Pierre, Ronsseray, Stéphane, Brasset, Emilie, Vaury, Chantal
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Argonaute Proteins - metabolism Development Biology Drosophila - genetics Drosophila - growth & development Drosophila - metabolism Drosophila Proteins - metabolism Female Gametogenesis Gene Silencing Genetics Life Sciences Molecular Biology Mutation Oogenesis - genetics Retroelements RNA, Small Interfering - metabolism Transgenes
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