Two Case Reports of Resensitization to Previous Chemotherapy with the Novel Hypoxia-Activated Hypomethylating Anticancer Agent RRx-001 in Metastatic Colorectal Cancer Patients

The development of chemoresistance is a persistent problem during the treatment of cancer. Although reversion or modification of acquired chemoresistance has been previously observed, no systematic exploration has been undertaken. Here, we report a case study of 2 male patients, 62 and 66 years old,...

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Veröffentlicht in:	Case reports in oncology 2014-01, Vol.7 (1), p.79-85
Hauptverfasser:	Reid, T., Dad, S., Korn, R., Oronsky, B., Knox, S., Scicinski, J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Epigenetic resensitization Hypoxia activation Oxidation Published: January 2014
Online-Zugang:	Volltext
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