Relation of mitochondrial oxygen consumption in peripheral blood mononuclear cells to vascular function in type 2 diabetes mellitus

Recent studies have shown mitochondrial dysfunction and increased production of reactive oxygen species in peripheral blood mononuclear cells (PBMCs) and endothelial cells from patients with diabetes mellitus. Mitochondria oxygen consumption is coupled to adenosine triphosphate (ATP) production and...

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Veröffentlicht in:	Vascular medicine (London, England) England), 2014-02, Vol.19 (1), p.67-74
Hauptverfasser:	Hartman, Mor-Li, Shirihai, Orian S, Holbrook, Monika, Xu, Guoquan, Kocherla, Marsha, Shah, Akash, Fetterman, Jessica L, Kluge, Matthew A, Frame, Alissa A, Hamburg, Naomi M, Vita, Joseph A
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Brachial Artery - metabolism Diabetes Mellitus, Type 2 - metabolism Diabetes Mellitus, Type 2 - physiopathology Endothelium, Vascular - metabolism Endothelium, Vascular - physiopathology Female Humans Leukocytes, Mononuclear - metabolism Male Middle Aged Mitochondria - metabolism Nitroglycerin - metabolism Oxygen Consumption - physiology
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