Harvest: an open platform for developing web-based biomedical data discovery and reporting applications

Biomedical researchers share a common challenge of making complex data understandable and accessible as they seek inherent relationships between attributes in disparate data types. Data discovery in this context is limited by a lack of query systems that efficiently show relationships between indivi...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Journal of the American Medical Informatics Association : JAMIA 2014-03, Vol.21 (2), p.379-383
Hauptverfasser: Pennington, Jeffrey W, Ruth, Byron, Italia, Michael J, Miller, Jeffrey, Wrazien, Stacey, Loutrel, Jennifer G, Crenshaw, E Bryan, White, Peter S
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 383
container_issue 2
container_start_page 379
container_title Journal of the American Medical Informatics Association : JAMIA
container_volume 21
creator Pennington, Jeffrey W
Ruth, Byron
Italia, Michael J
Miller, Jeffrey
Wrazien, Stacey
Loutrel, Jennifer G
Crenshaw, E Bryan
White, Peter S
description Biomedical researchers share a common challenge of making complex data understandable and accessible as they seek inherent relationships between attributes in disparate data types. Data discovery in this context is limited by a lack of query systems that efficiently show relationships between individual variables, but without the need to navigate underlying data models. We have addressed this need by developing Harvest, an open-source framework of modular components, and using it for the rapid development and deployment of custom data discovery software applications. Harvest incorporates visualizations of highly dimensional data in a web-based interface that promotes rapid exploration and export of any type of biomedical information, without exposing researchers to underlying data models. We evaluated Harvest with two cases: clinical data from pediatric cardiology and demonstration data from the OpenMRS project. Harvest's architecture and public open-source code offer a set of rapid application development tools to build data discovery applications for domain-specific biomedical data repositories. All resources, including the OpenMRS demonstration, can be found at http://harvest.research.chop.edu.
doi_str_mv 10.1136/amiajnl-2013-001825
format Article
fullrecord <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3932456</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1499137276</sourcerecordid><originalsourceid>FETCH-LOGICAL-c405t-27c5c75ad7c129c9a23ec9f6ef510d92cb19cb5c525785976116f8b380cf94083</originalsourceid><addsrcrecordid>eNpVkUtLxDAUhYMovn-BIFm6qebRNI0LQQZfILhRcBdu03SMpE1NOiP-ezPMKLpJAjnn3JN8CJ1Qck4pry6gd_A--IIRygtCaM3EFtqngslCyfJ1O59JJQtBmNxDBym9Z03FuNhFe6yknApK9tH8HuLSpukSw4DDaAc8epi6EHucF9zapfVhdMMcf9qmaCDZFjcu9LZ1BjxuYQLcumTC0savnNHiaMcQp5UDxtFn1eTCkI7QTgc-2ePNfohebm-eZ_fF49Pdw-z6sTAlEVPBpBFGCmiloUwZBYxbo7rKdrltq5hpqDKNMIIJWQslK0qrrm54TUynSlLzQ3S1zh0XTS5p7DBF8HqMrof4pQM4_f9mcG96HpaaK85KUeWAs01ADB-L_DO6z8-z3sNgwyJpWipFuWRyJeVrqYkhpWi73zGU6BUivUGkV4j0GlF2nf5t-Ov5YcK_AfkSkU4</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1499137276</pqid></control><display><type>article</type><title>Harvest: an open platform for developing web-based biomedical data discovery and reporting applications</title><source>MEDLINE</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>Oxford University Press Journals All Titles (1996-Current)</source><source>PubMed Central</source><creator>Pennington, Jeffrey W ; Ruth, Byron ; Italia, Michael J ; Miller, Jeffrey ; Wrazien, Stacey ; Loutrel, Jennifer G ; Crenshaw, E Bryan ; White, Peter S</creator><creatorcontrib>Pennington, Jeffrey W ; Ruth, Byron ; Italia, Michael J ; Miller, Jeffrey ; Wrazien, Stacey ; Loutrel, Jennifer G ; Crenshaw, E Bryan ; White, Peter S</creatorcontrib><description>Biomedical researchers share a common challenge of making complex data understandable and accessible as they seek inherent relationships between attributes in disparate data types. Data discovery in this context is limited by a lack of query systems that efficiently show relationships between individual variables, but without the need to navigate underlying data models. We have addressed this need by developing Harvest, an open-source framework of modular components, and using it for the rapid development and deployment of custom data discovery software applications. Harvest incorporates visualizations of highly dimensional data in a web-based interface that promotes rapid exploration and export of any type of biomedical information, without exposing researchers to underlying data models. We evaluated Harvest with two cases: clinical data from pediatric cardiology and demonstration data from the OpenMRS project. Harvest's architecture and public open-source code offer a set of rapid application development tools to build data discovery applications for domain-specific biomedical data repositories. All resources, including the OpenMRS demonstration, can be found at http://harvest.research.chop.edu.</description><identifier>ISSN: 1067-5027</identifier><identifier>EISSN: 1527-974X</identifier><identifier>DOI: 10.1136/amiajnl-2013-001825</identifier><identifier>PMID: 24131510</identifier><language>eng</language><publisher>England: BMJ Publishing Group</publisher><subject>Biomedical Research ; Case Report ; Computational Biology - methods ; Database Management Systems ; Databases, Factual ; Humans ; Internet ; Organizational Case Studies ; Ownership ; Software ; Translational Medical Research</subject><ispartof>Journal of the American Medical Informatics Association : JAMIA, 2014-03, Vol.21 (2), p.379-383</ispartof><rights>Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions 2014</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c405t-27c5c75ad7c129c9a23ec9f6ef510d92cb19cb5c525785976116f8b380cf94083</citedby><cites>FETCH-LOGICAL-c405t-27c5c75ad7c129c9a23ec9f6ef510d92cb19cb5c525785976116f8b380cf94083</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3932456/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3932456/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,27923,27924,53790,53792</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24131510$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Pennington, Jeffrey W</creatorcontrib><creatorcontrib>Ruth, Byron</creatorcontrib><creatorcontrib>Italia, Michael J</creatorcontrib><creatorcontrib>Miller, Jeffrey</creatorcontrib><creatorcontrib>Wrazien, Stacey</creatorcontrib><creatorcontrib>Loutrel, Jennifer G</creatorcontrib><creatorcontrib>Crenshaw, E Bryan</creatorcontrib><creatorcontrib>White, Peter S</creatorcontrib><title>Harvest: an open platform for developing web-based biomedical data discovery and reporting applications</title><title>Journal of the American Medical Informatics Association : JAMIA</title><addtitle>J Am Med Inform Assoc</addtitle><description>Biomedical researchers share a common challenge of making complex data understandable and accessible as they seek inherent relationships between attributes in disparate data types. Data discovery in this context is limited by a lack of query systems that efficiently show relationships between individual variables, but without the need to navigate underlying data models. We have addressed this need by developing Harvest, an open-source framework of modular components, and using it for the rapid development and deployment of custom data discovery software applications. Harvest incorporates visualizations of highly dimensional data in a web-based interface that promotes rapid exploration and export of any type of biomedical information, without exposing researchers to underlying data models. We evaluated Harvest with two cases: clinical data from pediatric cardiology and demonstration data from the OpenMRS project. Harvest's architecture and public open-source code offer a set of rapid application development tools to build data discovery applications for domain-specific biomedical data repositories. All resources, including the OpenMRS demonstration, can be found at http://harvest.research.chop.edu.</description><subject>Biomedical Research</subject><subject>Case Report</subject><subject>Computational Biology - methods</subject><subject>Database Management Systems</subject><subject>Databases, Factual</subject><subject>Humans</subject><subject>Internet</subject><subject>Organizational Case Studies</subject><subject>Ownership</subject><subject>Software</subject><subject>Translational Medical Research</subject><issn>1067-5027</issn><issn>1527-974X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpVkUtLxDAUhYMovn-BIFm6qebRNI0LQQZfILhRcBdu03SMpE1NOiP-ezPMKLpJAjnn3JN8CJ1Qck4pry6gd_A--IIRygtCaM3EFtqngslCyfJ1O59JJQtBmNxDBym9Z03FuNhFe6yknApK9tH8HuLSpukSw4DDaAc8epi6EHucF9zapfVhdMMcf9qmaCDZFjcu9LZ1BjxuYQLcumTC0savnNHiaMcQp5UDxtFn1eTCkI7QTgc-2ePNfohebm-eZ_fF49Pdw-z6sTAlEVPBpBFGCmiloUwZBYxbo7rKdrltq5hpqDKNMIIJWQslK0qrrm54TUynSlLzQ3S1zh0XTS5p7DBF8HqMrof4pQM4_f9mcG96HpaaK85KUeWAs01ADB-L_DO6z8-z3sNgwyJpWipFuWRyJeVrqYkhpWi73zGU6BUivUGkV4j0GlF2nf5t-Ov5YcK_AfkSkU4</recordid><startdate>20140301</startdate><enddate>20140301</enddate><creator>Pennington, Jeffrey W</creator><creator>Ruth, Byron</creator><creator>Italia, Michael J</creator><creator>Miller, Jeffrey</creator><creator>Wrazien, Stacey</creator><creator>Loutrel, Jennifer G</creator><creator>Crenshaw, E Bryan</creator><creator>White, Peter S</creator><general>BMJ Publishing Group</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20140301</creationdate><title>Harvest: an open platform for developing web-based biomedical data discovery and reporting applications</title><author>Pennington, Jeffrey W ; Ruth, Byron ; Italia, Michael J ; Miller, Jeffrey ; Wrazien, Stacey ; Loutrel, Jennifer G ; Crenshaw, E Bryan ; White, Peter S</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c405t-27c5c75ad7c129c9a23ec9f6ef510d92cb19cb5c525785976116f8b380cf94083</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Biomedical Research</topic><topic>Case Report</topic><topic>Computational Biology - methods</topic><topic>Database Management Systems</topic><topic>Databases, Factual</topic><topic>Humans</topic><topic>Internet</topic><topic>Organizational Case Studies</topic><topic>Ownership</topic><topic>Software</topic><topic>Translational Medical Research</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Pennington, Jeffrey W</creatorcontrib><creatorcontrib>Ruth, Byron</creatorcontrib><creatorcontrib>Italia, Michael J</creatorcontrib><creatorcontrib>Miller, Jeffrey</creatorcontrib><creatorcontrib>Wrazien, Stacey</creatorcontrib><creatorcontrib>Loutrel, Jennifer G</creatorcontrib><creatorcontrib>Crenshaw, E Bryan</creatorcontrib><creatorcontrib>White, Peter S</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Journal of the American Medical Informatics Association : JAMIA</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Pennington, Jeffrey W</au><au>Ruth, Byron</au><au>Italia, Michael J</au><au>Miller, Jeffrey</au><au>Wrazien, Stacey</au><au>Loutrel, Jennifer G</au><au>Crenshaw, E Bryan</au><au>White, Peter S</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Harvest: an open platform for developing web-based biomedical data discovery and reporting applications</atitle><jtitle>Journal of the American Medical Informatics Association : JAMIA</jtitle><addtitle>J Am Med Inform Assoc</addtitle><date>2014-03-01</date><risdate>2014</risdate><volume>21</volume><issue>2</issue><spage>379</spage><epage>383</epage><pages>379-383</pages><issn>1067-5027</issn><eissn>1527-974X</eissn><abstract>Biomedical researchers share a common challenge of making complex data understandable and accessible as they seek inherent relationships between attributes in disparate data types. Data discovery in this context is limited by a lack of query systems that efficiently show relationships between individual variables, but without the need to navigate underlying data models. We have addressed this need by developing Harvest, an open-source framework of modular components, and using it for the rapid development and deployment of custom data discovery software applications. Harvest incorporates visualizations of highly dimensional data in a web-based interface that promotes rapid exploration and export of any type of biomedical information, without exposing researchers to underlying data models. We evaluated Harvest with two cases: clinical data from pediatric cardiology and demonstration data from the OpenMRS project. Harvest's architecture and public open-source code offer a set of rapid application development tools to build data discovery applications for domain-specific biomedical data repositories. All resources, including the OpenMRS demonstration, can be found at http://harvest.research.chop.edu.</abstract><cop>England</cop><pub>BMJ Publishing Group</pub><pmid>24131510</pmid><doi>10.1136/amiajnl-2013-001825</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 1067-5027
ispartof Journal of the American Medical Informatics Association : JAMIA, 2014-03, Vol.21 (2), p.379-383
issn 1067-5027
1527-974X
language eng
recordid cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3932456
source MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Oxford University Press Journals All Titles (1996-Current); PubMed Central
subjects Biomedical Research
Case Report
Computational Biology - methods
Database Management Systems
Databases, Factual
Humans
Internet
Organizational Case Studies
Ownership
Software
Translational Medical Research
title Harvest: an open platform for developing web-based biomedical data discovery and reporting applications
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-08T21%3A07%3A39IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Harvest:%20an%20open%20platform%20for%20developing%20web-based%20biomedical%20data%20discovery%20and%20reporting%20applications&rft.jtitle=Journal%20of%20the%20American%20Medical%20Informatics%20Association%20:%20JAMIA&rft.au=Pennington,%20Jeffrey%20W&rft.date=2014-03-01&rft.volume=21&rft.issue=2&rft.spage=379&rft.epage=383&rft.pages=379-383&rft.issn=1067-5027&rft.eissn=1527-974X&rft_id=info:doi/10.1136/amiajnl-2013-001825&rft_dat=%3Cproquest_pubme%3E1499137276%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1499137276&rft_id=info:pmid/24131510&rfr_iscdi=true