A recurrent 11q aberration pattern characterizes a subset of MYC-negative high-grade B-cell lymphomas resembling Burkitt lymphoma

The genetic hallmark of Burkitt lymphoma (BL) is the t(8;14)(q24;q32) and its variants leading to activation of the MYC oncogene. It is a matter of debate whether true BL without MYC translocation exists. Here, we identified 59 lymphomas concordantly called BL by 2 gene expression classifiers among...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Blood 2014-02, Vol.123 (8), p.1187-1198
Hauptverfasser:	Salaverria, Itziar, Martin-Guerrero, Idoia, Wagener, Rabea, Kreuz, Markus, Kohler, Christian W., Richter, Julia, Pienkowska-Grela, Barbara, Adam, Patrick, Burkhardt, Birgit, Claviez, Alexander, Damm-Welk, Christine, Drexler, Hans G., Hummel, Michael, Jaffe, Elaine S., Küppers, Ralf, Lefebvre, Christine, Lisfeld, Jasmin, Löffler, Markus, Macleod, Roderick A.F., Nagel, Inga, Oschlies, Ilske, Rosolowski, Maciej, Russell, Robert B., Rymkiewicz, Grzegorz, Schindler, Detlev, Schlesner, Matthias, Scholtysik, René, Schwaenen, Carsten, Spang, Rainer, Szczepanowski, Monika, Trümper, Lorenz, Vater, Inga, Wessendorf, Swen, Klapper, Wolfram, Siebert, Reiner
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged B-Lymphocytes - physiology Burkitt Lymphoma - classification Burkitt Lymphoma - genetics Burkitt Lymphoma - pathology Cell Line Child Chromosomes, Human, Pair 11 Chromosomes, Human, Pair 14 Chromosomes, Human, Pair 8 Female Gene Expression Regulation, Neoplastic Genes, myc - genetics Humans Lymphoid Neoplasia Male Neoplasm Grading Recurrence Translocation, Genetic - genetics Young Adult
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!