Induction of polyploidy by nuclear fusion mechanism upon decreased expression of the nuclear envelope protein LAP2β in the human osteosarcoma cell line U2OS

Polyploidy has been recognized for many years as an important hallmark of cancer cells. Polyploid cells can arise through cell fusion, endoreplication and abortive cell cycle. The inner nuclear membrane protein LAP2β plays key roles in nuclear envelope breakdown and reassembly during mitosis, initia...

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Veröffentlicht in:	Molecular cytogenetics 2014-01, Vol.7 (1), p.9-9, Article 9
Hauptverfasser:	Ben-Shoshan, Shirley Oren, Simon, Amos J, Jacob-Hirsch, Jasmine, Shaklai, Sigal, Paz-Yaacov, Nurit, Amariglio, Ninette, Rechavi, Gideon, Trakhtenbrot, Luba
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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