Small heat shock proteins are necessary for heart migration and laterality determination in zebrafish

Small heat shock proteins (sHsps) regulate cellular functions not only under stress, but also during normal development, when they are expressed in organ-specific patterns. Here we demonstrate that two small heat shock proteins expressed in embryonic zebrafish heart, hspb7 and hspb12, have roles in...

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Veröffentlicht in:	Developmental biology 2013-12, Vol.384 (2), p.166-180
Hauptverfasser:	Lahvic, Jamie L., Ji, Yongchang, Marin, Paloma, Zuflacht, Jonah P., Springel, Mark W., Wosen, Jonathan E., Davis, Leigh, Hutson, Lara D., Amack, Jeffrey D., Marvin, Martha J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Base Sequence Body Patterning - physiology brain Cardia bifida Cilia Danio rerio DNA Primers Freshwater gene expression genes heart Heart - embryology heat shock proteins Heat-Shock Proteins, Small - genetics Heat-Shock Proteins, Small - physiology Kupffer's vesicle Left–right asymmetry Microscopy, Electron, Transmission penetrance Polymerase Chain Reaction protein synthesis Small heat shock protein Yolk syncytial layer Zebrafish - embryology
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