A randomized, double-blind, placebo-controlled, multicentre study to assess haemodynamic effects of serelaxin in patients with acute heart failure

The aim of this study was to evaluate the haemodynamic effects of serelaxin (30 µg/kg/day 20-h infusion and 4-h post-infusion period) in patients with acute heart failure (AHF). This double-blind, multicentre study randomized 71 AHF patients with pulmonary capillary wedge pressure (PCWP) ≥ 18 mmHg,...

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Veröffentlicht in:	European heart journal 2014-02, Vol.35 (7), p.431-441
Hauptverfasser:	Ponikowski, Piotr, Mitrovic, Veselin, Ruda, Mikhail, Fernandez, Alberto, Voors, Adriaan A, Vishnevsky, Alexander, Cotter, Gad, Milo, Olga, Laessing, Ute, Zhang, Yiming, Dahlke, Marion, Zymlinski, Robert, Metra, Marco
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Analysis of Variance Blood Pressure - drug effects Cardiotonic Agents - administration & dosage Cardiotonic Agents - pharmacology Double-Blind Method Female Glomerular Filtration Rate - drug effects Heart Failure - drug therapy Heart Failure - physiopathology Hemodynamics - drug effects Humans Infusions, Intravenous Male Pulmonary Wedge Pressure - drug effects Recombinant Proteins - administration & dosage Recombinant Proteins - pharmacology Relaxin - administration & dosage Relaxin - pharmacology Track Clinical Research Vascular Resistance - drug effects
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