Pretreatment of Gymnema sylvestre revealed the protection against acetic acid-induced ulcerative colitis in rats

Overproduction of free radicals and decreased antioxidant capacity are well-known risk factors for inflammatory bowel diseases. Gymnema sylvestre (GS) leaves extract is distinguished for its anti-diabetic, antioxidant and anti-inflammatory properties. Present study is designed to evaluate the preven...

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Veröffentlicht in:	BMC complementary and alternative medicine 2014-02, Vol.14 (1), p.49-49, Article 49
Hauptverfasser:	Aleisa, Abdulaziz M, Al-Rejaie, Salim S, Abuohashish, Hatem M, Ola, Mohammed S, Parmar, Mihir Y, Ahmed, Mohammed M
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetic Acid Acids Animals Anti-Inflammatory Agents - pharmacology Anti-Inflammatory Agents - therapeutic use Antioxidants Antioxidants - metabolism Antioxidants - pharmacology Antioxidants - therapeutic use Care and treatment Catalase - metabolism Colitis - chemically induced Colitis - metabolism Colitis - prevention & control Colitis, Ulcerative - chemically induced Colitis, Ulcerative - metabolism Colitis, Ulcerative - prevention & control Colon - drug effects Colon - metabolism Cytokines Free radicals Glutathione - metabolism Gymnema sylvestre Health aspects Herbal medicine Inflammatory bowel disease Instrument industry Interleukin-1beta - metabolism Interleukin-6 - metabolism Interleukins Lipid peroxidation Male Oxidative stress Pathogenesis Pharmaceutical sciences Pharmacy Phytotherapy Plant Extracts - pharmacology Plant Extracts - therapeutic use Plant Leaves Proteins Rats, Wistar Risk factors Rodents Studies Superoxide Dismutase - metabolism Thiobarbituric Acid Reactive Substances Tumor Necrosis Factor-alpha - metabolism Ulcerative colitis
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