Contralateral mastectomy and survival after breast cancer in carriers of BRCA1 and BRCA2 mutations: retrospective analysis

Objective To compare the survival rates of women with BRCA associated breast cancer who did and did not undergo mastectomy of the contralateral breast. Design Retrospective analysis. Setting 12 cancer genetics clinics. Participants 390 women with a family history of stage I or II breast cancer who w...

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Veröffentlicht in:	BMJ (Online) 2014-02, Vol.348 (feb11 9), p.g226-g226
Hauptverfasser:	Metcalfe, Kelly, Gershman, Shelley, Ghadirian, Parviz, Lynch, Henry T, Snyder, Carrie, Tung, Nadine, Kim-Sing, Charmaine, Eisen, Andrea, Foulkes, William D, Rosen, Barry, Sun, Ping, Narod, Steven A
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult BRCA1 protein BRCA1 Protein - genetics BRCA1 Protein - metabolism BRCA2 protein BRCA2 Protein - genetics BRCA2 Protein - metabolism Breast cancer Breast Neoplasms - genetics Breast Neoplasms - mortality Breast Neoplasms - surgery Canada - epidemiology DNA, Neoplasm - genetics Female Forecasting Health risk assessment Humans Mammography Mastectomy Mastectomy - methods Mastectomy - mortality Medical records Middle Aged Mortality Mutation Neoplasm Staging Retrospective Studies Survival Survival Rate - trends United States - epidemiology Womens health
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