Intraluminal acid activates esophageal nodose C fibers after mast cell activation

Acid reflux in the esophagus can induce esophageal painful sensations such as heartburn and noncardiac chest pain. The mechanisms underlying acid-induced esophageal nociception are not clearly understood. In our previous studies, we characterized esophageal vagal nociceptive afferents and defined th...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	American journal of physiology: Gastrointestinal and liver physiology 2014-02, Vol.306 (3), p.G200-G207
Hauptverfasser:	Zhang, Shizhong, Liu, Zhenyu, Heldsinger, Andrea, Owyang, Chung, Yu, Shaoyong
Format:	Artikel
Sprache:	eng
Schlagworte:	Acids - pharmacology Animals Capsaicin - pharmacology Cellular biology Esophagus Esophagus - drug effects Esophagus - innervation Esophagus - metabolism Evoked Potentials - physiology Gastroesophageal reflux Guinea Pigs Male Mast Cells - drug effects Mast Cells - metabolism Nerve Fibers, Unmyelinated - drug effects Nerve Fibers, Unmyelinated - metabolism Neurons Neuroregulation and Motility Nodose Ganglion - cytology Ovalbumin - pharmacology Physiology Protein expression Stimulation, Chemical Vagus Nerve - drug effects Vagus Nerve - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!