Tissue engineering is a promising method for the repair of spinal cord injuries (Review)

Spinal cord injury (SCI) may lead to a devastating and permanent loss of neurological function, which may place a great economic burden on the family of the patient and society. Methods for reducing the death of neuronal cells, inhibiting immune and inflammatory reactions, and promoting the growth o...

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Veröffentlicht in:Experimental and therapeutic medicine 2014-03, Vol.7 (3), p.523-528
Hauptverfasser: JI, WENCHEN, HU, SHOUYE, ZHOU, JIAO, WANG, GANG, WANG, KUNZHENG, ZHANG, YUELIN
Format: Artikel
Sprache:eng
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Zusammenfassung:Spinal cord injury (SCI) may lead to a devastating and permanent loss of neurological function, which may place a great economic burden on the family of the patient and society. Methods for reducing the death of neuronal cells, inhibiting immune and inflammatory reactions, and promoting the growth of axons in order to build up synapses with the target cells are the focus of current research. Target cells are located in the damaged spinal cord which create a connect with the scaffold. As tissue engineering technology is developed for use in a variety of different areas, particularly the biomedical field, a clear understanding of the mechanisms of tissue engineering is important. This review establishes how this technology may be used in basic experiments with regard to SCI and considers its potential future clinical use.
ISSN:1792-0981
1792-1015
DOI:10.3892/etm.2013.1454