Coronary heart disease alters intercellular communication by modifying microparticle-mediated microRNA transport

•The circulating miRNA transport profile is altered in coronary heart disease (CHD) patients.•CHD is associated with decreased miRNA loading of microparticles (MPs).•CHD is associated with decreased transfer of miRNA from MPs to recipient cells.•MPs isolated from CHD patients have diminished capacit...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	FEBS letters 2013-11, Vol.587 (21), p.3456-3463
Hauptverfasser:	Finn, Nnenna A., Eapen, Danny, Manocha, Pankaj, Al Kassem, Hatem, Lassegue, Bernard, Ghasemzadeh, Nima, Quyyumi, Arshed, Searles, Charles D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult aggregated protein Atherosclerosis Binding Sites Biological Transport - physiology Carrier Proteins - genetics Carrier Proteins - metabolism Cell Communication CHD coronary disease Coronary Disease - genetics Coronary Disease - metabolism Coronary heart disease Del-1 Developmental endothelial locus-1 Exo exosomes Female Human Umbilical Vein Endothelial Cells Humans Intercellular signaling lipoprotein Male Microparticles MicroRNA MicroRNAs - metabolism Middle Aged MP/MPs patients Real-Time Polymerase Chain Reaction risk factor
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!