Induction of the liver cancer-down-regulated long noncoding RNA uc002mbe.2 mediates trichostatin-induced apoptosis of liver cancer cells

Differential expression of long non-coding RNAs (lncRNAs) plays critical roles in hepatocarcinogenesis. Considerable attention has focused on the antitumor effect of histone deacetylase inhibitor (Trichostatin A, TSA) as well as the coding gene expression-induced apoptosis of cancer cells. However,...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Biochemical pharmacology 2013-06, Vol.85 (12), p.1761-1769
Hauptverfasser:	Yang, Hui, Zhong, Yun, Xie, Hui, Lai, XiaoBo, Xu, Miqing, Nie, Yuqiang, Liu, Shiming, Wan, Yu-Jui Yvonne
Format:	Artikel
Sprache:	eng
Schlagworte:	apoptosis Apoptosis - drug effects Apoptosis - physiology carcinogenesis Carcinoma, Hepatocellular - drug therapy Carcinoma, Hepatocellular - genetics Carcinoma, Hepatocellular - pathology Cell Line, Tumor correlation Down-Regulation - drug effects Down-Regulation - physiology gene expression regulation Gene Expression Regulation, Neoplastic - drug effects Gene Expression Regulation, Neoplastic - physiology genes Hep G2 Cells Hepatocellular carcinoma hepatocytes hepatoma histone deacetylase Histone deacetylase inhibitor Humans Hydroxamic Acids - antagonists & inhibitors Hydroxamic Acids - pharmacology Hydroxamic Acids - therapeutic use Liver Liver cancer Liver Neoplasms - drug therapy Liver Neoplasms - genetics Liver Neoplasms - pathology Long noncoding RNA non-coding RNA pharmacology quantitative polymerase chain reaction RNA, Long Noncoding - antagonists & inhibitors RNA, Long Noncoding - biosynthesis RNA, Long Noncoding - physiology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!