Gene expression profiles of inflammatory breast cancer: correlation with response to neoadjuvant chemotherapy and metastasis-free survival

Inflammatory breast cancer (IBC) is an aggressive disease. To date, no molecular feature reliably predicts either the response to chemotherapy (CT) or the survival. Using DNA microarrays, we searched for multigene predictors. The World IBC Consortium generated whole-genome expression profiles of 137...

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Veröffentlicht in:	Annals of oncology 2014-02, Vol.25 (2), p.358-365
Hauptverfasser:	Bertucci, F., Ueno, N.T., Finetti, P., Vermeulen, P., Lucci, A., Robertson, F.M., Marsan, M., Iwamoto, T., Krishnamurthy, S., Masuda, H., Van Dam, P., Woodward, W.A., Cristofanilli, M., Reuben, J.M., Dirix, L., Viens, P., Symmans, W.F., Birnbaum, D., Van Laere, S.J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Antineoplastic agents Biological and medical sciences Carcinoma, Ductal, Breast - drug therapy Carcinoma, Ductal, Breast - metabolism Carcinoma, Ductal, Breast - mortality Carcinoma, Ductal, Breast - secondary Chemotherapy, Adjuvant Disease-Free Survival Estrogen Receptor alpha - genetics Estrogen Receptor alpha - metabolism Female gene expression Gene Expression Profiling Gynecology. Andrology. Obstetrics Humans inflammatory breast cancer Inflammatory Breast Neoplasms - drug therapy Inflammatory Breast Neoplasms - metabolism Inflammatory Breast Neoplasms - mortality Inflammatory Breast Neoplasms - pathology Kaplan-Meier Estimate Mammary gland diseases Medical sciences Middle Aged Multiple tumors. Solid tumors. Tumors in childhood (general aspects) Neoadjuvant Therapy Original Pharmacology. Drug treatments profiling prognosis Receptor, ErbB-2 - genetics Receptor, ErbB-2 - metabolism response to chemotherapy Transcriptome Tumors
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