Genome-wide association study implicates NDST3 in schizophrenia and bipolar disorder

Schizophrenia and bipolar disorder are major psychiatric disorders with high heritability and overlapping genetic variance. Here we perform a genome-wide association study in an ethnically homogeneous cohort of 904 schizophrenia cases and 1,640 controls drawn from the Ashkenazi Jewish population. We...

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Veröffentlicht in:	Nature communications 2013-11, Vol.4 (1), p.2739-2739, Article 2739
Hauptverfasser:	Lencz, Todd, Guha, Saurav, Liu, Chunyu, Rosenfeld, Jeffrey, Mukherjee, Semanti, DeRosse, Pamela, John, Majnu, Cheng, Lijun, Zhang, Chunling, Badner, Judith A., Ikeda, Masashi, Iwata, Nakao, Cichon, Sven, Rietschel, Marcella, Nöthen, Markus M., Cheng, A.T.A., Hodgkinson, Colin, Yuan, Qiaoping, Kane, John M., Lee, Annette T., Pisanté, Anne, Gregersen, Peter K., Pe’er, Itsik, Malhotra, Anil K., Goldman, David, Darvasi, Ariel
Format:	Artikel
Sprache:	eng
Schlagworte:	631/208/205/2138 692/420/2489/144 692/699/476/1333 692/699/476/1799 Bipolar Disorder - genetics Gene Expression Regulation Genetic Predisposition to Disease Genome, Human Humanities and Social Sciences Humans Jews - genetics multidisciplinary Odds Ratio Polymorphism, Single Nucleotide Schizophrenia - genetics Science Science (multidisciplinary) Sulfotransferases - genetics Sulfotransferases - metabolism
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