Sonoporation as an enhancing method for boron neutron capture therapy for squamous cell carcinomas

Boron neutron capture therapy (BNCT) is a selective radiotherapy that is dependent on the accumulation of ¹⁰B compound in tumors. Low-intensity ultrasound produces a transient pore on cell membranes, sonoporation, which enables extracellular materials to enter cells. The effect of sonoporation on BN...

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Veröffentlicht in:	Radiation oncology (London, England) England), 2013-12, Vol.8 (1), p.280-280, Article 280
Hauptverfasser:	Yamatomo, Naofumi, Iwagami, Takaki, Kato, Itsuro, Masunaga, Shin-Ichiro, Sakurai, Yoshinori, Iwai, Soichi, Nakazawa, Mitsuhiro, Ono, Koji, Yura, Yoshiaki
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Aqueous solutions Boron Boron Compounds - chemistry Boron Neutron Capture Therapy - methods Boron-neutron capture therapy Cancer therapies Carcinoma, Squamous Cell - pathology Carcinoma, Squamous Cell - radiotherapy Care and treatment Cell Line, Tumor Cell Membrane - radiation effects Experiments Female Gamma rays Head & neck cancer Health aspects Humans Ionizing radiation Isotopes - chemistry Mice Mice, Inbred BALB C Mice, Nude Microbubbles Mouth Neoplasms - pathology Mouth Neoplasms - radiotherapy Neoplasm Transplantation Neutrons Patient outcomes Pharmaceutical industry Phenylalanine - analogs & derivatives Phenylalanine - chemistry Radiation therapy Radiotherapy - methods Squamous cell carcinoma Surgery Tumors Ultrasonic imaging Ultrasonics - methods
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