Tumour-infiltrating lymphocytes predict response to definitive chemoradiotherapy in head and neck cancer

Background: We aimed to investigate the prognostic value of tumour-infiltrating lymphocytes’ (TILs) expression in pretreatment specimens from patients with head and neck squamous cell carcinoma (HNSCC) treated with definitive chemoradiotherapy (CRT). Methods: The prevalence of CD3+, CD8+, CD4+ and F...

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Veröffentlicht in:	British journal of cancer 2014-01, Vol.110 (2), p.501-509
Hauptverfasser:	Balermpas, P, Michel, Y, Wagenblast, J, Seitz, O, Weiss, C, Rödel, F, Rödel, C, Fokas, E
Format:	Artikel
Sprache:	eng
Schlagworte:	692/699/67/1059/485 692/699/67/1059/99 692/699/67/1536 692/700/1750 Biological and medical sciences Biomedical and Life Sciences Biomedicine Biopsy Cancer Research Cancer therapies Carcinoma, Squamous Cell - drug therapy Carcinoma, Squamous Cell - pathology Carcinoma, Squamous Cell - radiotherapy Carcinoma, Squamous Cell - therapy Chemoradiotherapy Chemotherapy Disease Progression Drug Resistance Epidemiology Female Head & neck cancer Head and Neck Neoplasms - drug therapy Head and Neck Neoplasms - pathology Head and Neck Neoplasms - radiotherapy Head and Neck Neoplasms - therapy Human papillomavirus Humans Immune system Immunohistochemistry Lymphocytes Lymphocytes, Tumor-Infiltrating - immunology Lymphocytes, Tumor-Infiltrating - pathology Male Medical prognosis Medical sciences Metastasis Middle Aged Molecular Diagnostics Molecular Medicine Multiple tumors. Solid tumors. Tumors in childhood (general aspects) Multivariate analysis Oncology Otorhinolaryngology (head neck, general aspects and miscellaneous) Otorhinolaryngology. Stomatology Prognosis Radiation therapy Squamous Cell Carcinoma of Head and Neck Tumors
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