Exploiting functional domains of GRK2/3 to alter the competitive balance of pro‐ and anticontractile signaling in airway smooth muscle
To clarify the potential utility of targeting GRK2/3‐mediated desensitization as a means of manipulating airway smooth muscle (ASM) contractile state, we assessed the specificity of GRK2/3 regulation of procontractile and relaxant G‐protein‐coupled receptors in ASM. Functional domains of GRK2/3 were...
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Veröffentlicht in: | The FASEB journal 2014-02, Vol.28 (2), p.956-965 |
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Hauptverfasser: | , , , , , , , , |
Format: | Artikel |
Sprache: | eng |
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