Membrane Site Modified on Induction of the Transformation of Lymphocytes by Periodate

Lymphocytes isolated from different sources undergo blastogenesis after mild treatment with periodate. Incubation of mouse spleen lymphocytes with neuraminidase or papain markedly reduces their response to periodate. Transformation induced by concanavalin A of the enzymically treated cells is not im...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 1972-11, Vol.69 (11), p.3207-3210
Hauptverfasser:	Novogrodsky, Abraham, Katchalski, Ephraim
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Binding Sites - drug effects Biological Sciences: Biochemistry Borohydrides Borohydrides - pharmacology Cell Membrane - drug effects Cell Membrane - metabolism Cell membranes Chemical suspensions Concanavalin A - pharmacology Cultured cells DNA - biosynthesis Enzymes Female Hydroxylamines - pharmacology Lymphocyte activation Lymphocyte Activation - drug effects Lymphocytes Lymphocytes - cytology Lymphocytes - metabolism Mice Neuraminic Acids - pharmacology Neuraminidase - metabolism Neurons Nickel Papain - pharmacology Periodic Acid - pharmacology Radioisotopes Semicarbazides Semicarbazides - pharmacology Sodium - pharmacology Spleen - cytology Spleen cells Thymidine - metabolism Tritium
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