Systemic immunity influences hearing preservation in cochlear implantation

To determine whether a systemic immune response influences hearing thresholds and tissue response after cochlear implantation of hearing guinea pigs. Guinea pigs were inoculated with sterile antigen (Keyhole limpet hemocyanin) 3 weeks before cochlear implantation. Pure-tone auditory brainstem respon...

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Veröffentlicht in:	Otology & neurotology 2012-06, Vol.33 (4), p.532-538
Hauptverfasser:	Souter, Melanie, Eastwood, Hayden, Marovic, Paul, Kel, Gordana, Wongprasartsuk, Sarin, Ryan, Allen F, O'Leary, Stephen John
Format:	Artikel
Sprache:	eng
Schlagworte:	Adjuvants, Immunologic - pharmacology Animals Anti-Inflammatory Agents - pharmacology Audiometry, Pure-Tone Auditory Threshold - drug effects Cochlear Implantation - adverse effects Cochlear Implants - adverse effects Dexamethasone - pharmacology Disease Models, Animal Drug Administration Routes Guinea Pigs Hearing Loss - drug therapy Hearing Loss - immunology Hemocyanins - immunology Hemocyanins - pharmacology Round Window, Ear - drug effects
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