Evaluation of Calretinin expression in Ameloblastoma and Non-Neoplastic Odontogenic Cysts – An immunohistochemical study
Background: Calretinin a 29-kDa calcium binding protein is expressed widely in normal human tissue and tumours including amelobastoma. The objective of this study was to determine calretinin expression in heamatoxylin and eosin diagnosed cases of ameloblastoma and non-neoplastic odontogenic cysts. M...
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| Veröffentlicht in: | Journal of international oral health 2013-12, Vol.5 (6), p.42-48 |
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| creator | D’Silva, Shaloom Sumathi, M K Balaji, N Shetty, Nisha K N Pramod, K M Cheeramelil, Jacob |
| description | Background:
Calretinin a 29-kDa calcium binding protein is expressed widely in normal human tissue and tumours including amelobastoma. The objective of this study was to determine calretinin expression in heamatoxylin and eosin diagnosed cases of ameloblastoma and non-neoplastic odontogenic cysts.
Materials & Methods:
The lining epithelium in 3 cases of radicular cysts, 5 cases of odontogenic keratocysts, 5 cases of dentigerous cysts and 11 cases of ameloblastomas were examined for expression of calretinin.
Results:
No positive epithelial staining was observed in radicular and dentigerous cysts. In comparison, however 100% of cases of ameloblastomas and 40% of cases of odontogenic karatocysts showed positive calretinin expression.
Conclusion:
Calretinin may be a specific immunohistochemical marker for ameloblastoma. If there is any possible relation between calretinin expression and neural origin of the odontogenic epithelium and its neoplastic transformation and if calretinin could be used as an early marker to predict the tendency of neoplastic change of odontogenic epithelium could be answered through further researches.
How to cite this article:
D’Silva S, Sumathi MK, Balaji N, Shetty NK, Pramod KM, Cheeramelil J. Evaluation of Calretinin expression in Ameloblastoma and Non-Neoplastic Odontogenic Cysts – An immunohistochemical study.
J Int Oral Health 2013; 5(6):42-8
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| format | Article |
| fullrecord | <record><control><sourceid>pubmedcentral</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3895716</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>pubmedcentral_primary_oai_pubmedcentral_nih_gov_3895716</sourcerecordid><originalsourceid>FETCH-pubmedcentral_primary_oai_pubmedcentral_nih_gov_38957163</originalsourceid><addsrcrecordid>eNqlTEtOwzAUtBCIVtA7-AKRkjSfZoNURUWsyoa99Zq8Nkb2e5HtVIQVd-CGnARX6oY1s5mfZm7EMm3qKsnqprm96rrINwux8v49jajSvCjKe7HIi6wsqzRbis_dGcwEQTNJPsoWjMOgSZPEj9Gh95ciuq1FwwcDPrAFCdTLPVOyRx4vme7ka88U-IQUdTv74OXP17fcxrG1E_Gg47Ib0OoOjPRh6udHcXcE43F15Qfx9Lx7a1-ScTpY7Duk4MCo0WkLblYMWv1tSA_qxGe13jRlnVXrfx_8AtMaazQ</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>Evaluation of Calretinin expression in Ameloblastoma and Non-Neoplastic Odontogenic Cysts – An immunohistochemical study</title><source>EZB-FREE-00999 freely available EZB journals</source><source>PubMed Central</source><creator>D’Silva, Shaloom ; Sumathi, M K ; Balaji, N ; Shetty, Nisha K N ; Pramod, K M ; Cheeramelil, Jacob</creator><creatorcontrib>D’Silva, Shaloom ; Sumathi, M K ; Balaji, N ; Shetty, Nisha K N ; Pramod, K M ; Cheeramelil, Jacob</creatorcontrib><description>Background:
Calretinin a 29-kDa calcium binding protein is expressed widely in normal human tissue and tumours including amelobastoma. The objective of this study was to determine calretinin expression in heamatoxylin and eosin diagnosed cases of ameloblastoma and non-neoplastic odontogenic cysts.
Materials & Methods:
The lining epithelium in 3 cases of radicular cysts, 5 cases of odontogenic keratocysts, 5 cases of dentigerous cysts and 11 cases of ameloblastomas were examined for expression of calretinin.
Results:
No positive epithelial staining was observed in radicular and dentigerous cysts. In comparison, however 100% of cases of ameloblastomas and 40% of cases of odontogenic karatocysts showed positive calretinin expression.
Conclusion:
Calretinin may be a specific immunohistochemical marker for ameloblastoma. If there is any possible relation between calretinin expression and neural origin of the odontogenic epithelium and its neoplastic transformation and if calretinin could be used as an early marker to predict the tendency of neoplastic change of odontogenic epithelium could be answered through further researches.
How to cite this article:
D’Silva S, Sumathi MK, Balaji N, Shetty NK, Pramod KM, Cheeramelil J. Evaluation of Calretinin expression in Ameloblastoma and Non-Neoplastic Odontogenic Cysts – An immunohistochemical study.
J Int Oral Health 2013; 5(6):42-8
.</description><identifier>ISSN: 0976-7428</identifier><identifier>EISSN: 0976-1799</identifier><identifier>PMID: 24155601</identifier><identifier>PMID: 24453443</identifier><language>eng</language><publisher>International Society of Preventive and Community Dentistry</publisher><subject>Public Health Dentistry</subject><ispartof>Journal of international oral health, 2013-12, Vol.5 (6), p.42-48</ispartof><rights>J. Int Oral Health 2013 2013</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3895716/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3895716/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,727,780,784,885,53791,53793</link.rule.ids></links><search><creatorcontrib>D’Silva, Shaloom</creatorcontrib><creatorcontrib>Sumathi, M K</creatorcontrib><creatorcontrib>Balaji, N</creatorcontrib><creatorcontrib>Shetty, Nisha K N</creatorcontrib><creatorcontrib>Pramod, K M</creatorcontrib><creatorcontrib>Cheeramelil, Jacob</creatorcontrib><title>Evaluation of Calretinin expression in Ameloblastoma and Non-Neoplastic Odontogenic Cysts – An immunohistochemical study</title><title>Journal of international oral health</title><description>Background:
Calretinin a 29-kDa calcium binding protein is expressed widely in normal human tissue and tumours including amelobastoma. The objective of this study was to determine calretinin expression in heamatoxylin and eosin diagnosed cases of ameloblastoma and non-neoplastic odontogenic cysts.
Materials & Methods:
The lining epithelium in 3 cases of radicular cysts, 5 cases of odontogenic keratocysts, 5 cases of dentigerous cysts and 11 cases of ameloblastomas were examined for expression of calretinin.
Results:
No positive epithelial staining was observed in radicular and dentigerous cysts. In comparison, however 100% of cases of ameloblastomas and 40% of cases of odontogenic karatocysts showed positive calretinin expression.
Conclusion:
Calretinin may be a specific immunohistochemical marker for ameloblastoma. If there is any possible relation between calretinin expression and neural origin of the odontogenic epithelium and its neoplastic transformation and if calretinin could be used as an early marker to predict the tendency of neoplastic change of odontogenic epithelium could be answered through further researches.
How to cite this article:
D’Silva S, Sumathi MK, Balaji N, Shetty NK, Pramod KM, Cheeramelil J. Evaluation of Calretinin expression in Ameloblastoma and Non-Neoplastic Odontogenic Cysts – An immunohistochemical study.
J Int Oral Health 2013; 5(6):42-8
.</description><subject>Public Health Dentistry</subject><issn>0976-7428</issn><issn>0976-1799</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><recordid>eNqlTEtOwzAUtBCIVtA7-AKRkjSfZoNURUWsyoa99Zq8Nkb2e5HtVIQVd-CGnARX6oY1s5mfZm7EMm3qKsnqprm96rrINwux8v49jajSvCjKe7HIi6wsqzRbis_dGcwEQTNJPsoWjMOgSZPEj9Gh95ciuq1FwwcDPrAFCdTLPVOyRx4vme7ka88U-IQUdTv74OXP17fcxrG1E_Gg47Ib0OoOjPRh6udHcXcE43F15Qfx9Lx7a1-ScTpY7Duk4MCo0WkLblYMWv1tSA_qxGe13jRlnVXrfx_8AtMaazQ</recordid><startdate>20131201</startdate><enddate>20131201</enddate><creator>D’Silva, Shaloom</creator><creator>Sumathi, M K</creator><creator>Balaji, N</creator><creator>Shetty, Nisha K N</creator><creator>Pramod, K M</creator><creator>Cheeramelil, Jacob</creator><general>International Society of Preventive and Community Dentistry</general><scope>5PM</scope></search><sort><creationdate>20131201</creationdate><title>Evaluation of Calretinin expression in Ameloblastoma and Non-Neoplastic Odontogenic Cysts – An immunohistochemical study</title><author>D’Silva, Shaloom ; Sumathi, M K ; Balaji, N ; Shetty, Nisha K N ; Pramod, K M ; Cheeramelil, Jacob</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-pubmedcentral_primary_oai_pubmedcentral_nih_gov_38957163</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>Public Health Dentistry</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>D’Silva, Shaloom</creatorcontrib><creatorcontrib>Sumathi, M K</creatorcontrib><creatorcontrib>Balaji, N</creatorcontrib><creatorcontrib>Shetty, Nisha K N</creatorcontrib><creatorcontrib>Pramod, K M</creatorcontrib><creatorcontrib>Cheeramelil, Jacob</creatorcontrib><collection>PubMed Central (Full Participant titles)</collection><jtitle>Journal of international oral health</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>D’Silva, Shaloom</au><au>Sumathi, M K</au><au>Balaji, N</au><au>Shetty, Nisha K N</au><au>Pramod, K M</au><au>Cheeramelil, Jacob</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Evaluation of Calretinin expression in Ameloblastoma and Non-Neoplastic Odontogenic Cysts – An immunohistochemical study</atitle><jtitle>Journal of international oral health</jtitle><date>2013-12-01</date><risdate>2013</risdate><volume>5</volume><issue>6</issue><spage>42</spage><epage>48</epage><pages>42-48</pages><issn>0976-7428</issn><eissn>0976-1799</eissn><abstract>Background:
Calretinin a 29-kDa calcium binding protein is expressed widely in normal human tissue and tumours including amelobastoma. The objective of this study was to determine calretinin expression in heamatoxylin and eosin diagnosed cases of ameloblastoma and non-neoplastic odontogenic cysts.
Materials & Methods:
The lining epithelium in 3 cases of radicular cysts, 5 cases of odontogenic keratocysts, 5 cases of dentigerous cysts and 11 cases of ameloblastomas were examined for expression of calretinin.
Results:
No positive epithelial staining was observed in radicular and dentigerous cysts. In comparison, however 100% of cases of ameloblastomas and 40% of cases of odontogenic karatocysts showed positive calretinin expression.
Conclusion:
Calretinin may be a specific immunohistochemical marker for ameloblastoma. If there is any possible relation between calretinin expression and neural origin of the odontogenic epithelium and its neoplastic transformation and if calretinin could be used as an early marker to predict the tendency of neoplastic change of odontogenic epithelium could be answered through further researches.
How to cite this article:
D’Silva S, Sumathi MK, Balaji N, Shetty NK, Pramod KM, Cheeramelil J. Evaluation of Calretinin expression in Ameloblastoma and Non-Neoplastic Odontogenic Cysts – An immunohistochemical study.
J Int Oral Health 2013; 5(6):42-8
.</abstract><pub>International Society of Preventive and Community Dentistry</pub><pmid>24155601</pmid><pmid>24453443</pmid></addata></record> |
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| subjects | Public Health Dentistry |
| title | Evaluation of Calretinin expression in Ameloblastoma and Non-Neoplastic Odontogenic Cysts – An immunohistochemical study |
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