The unfolded protein response is activated in disease-affected brain regions in progressive supranuclear palsy and Alzheimer's disease

Progressive supranuclear palsy (PSP) is a neurodegenerative disorder pathologically characterized by intracellular tangles of hyperphosphorylated tau protein distributed throughout the neocortex, basal ganglia, and brainstem. A genome-wide association study identified EIF2AK3 as a risk factor for PS...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Acta neuropathologica communications 2013-07, Vol.1 (1), p.31-31, Article 31
Hauptverfasser:	Stutzbach, Lauren D, Xie, Sharon X, Naj, Adam C, Albin, Roger, Gilman, Sid, Lee, Virginia M Y, Trojanowski, John Q, Devlin, Bernie, Schellenberg, Gerard D
Format:	Artikel
Sprache:	eng
Schlagworte:	Advertising executives Aged Aging - genetics Aging - metabolism Aging - pathology Alzheimer Disease - genetics Alzheimer Disease - metabolism Alzheimer Disease - pathology Amyotrophic lateral sclerosis Analysis Brain - metabolism Brain - pathology eIF-2 Kinase - genetics eIF-2 Kinase - metabolism Female Genetic aspects Genetic Predisposition to Disease Genetic susceptibility Haplotypes Humans Male Medical research Medicine, Experimental Middle Aged Physiological aspects Polymorphism, Single Nucleotide Progressive supranuclear palsy Protein folding Protein kinases Risk factors Supranuclear Palsy, Progressive - genetics Supranuclear Palsy, Progressive - metabolism Supranuclear Palsy, Progressive - pathology tau Proteins - metabolism Unfolded Protein Response
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!