Treatment of children with high grade glioma with nimotuzumab: A 5-y institutional experience

Brain tumors are a major cause of cancer-related mortality in children. Overexpression of epidermal growth factor receptor (EGFR) is detected in pediatric brain tumors and receptor density appears to increase with tumor grading. Nimotuzumab is an IgG1 antibody that targets EGFR. Twenty-three childre...

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Veröffentlicht in:mAbs 2013-03, Vol.5 (2), p.202-207
Hauptverfasser: Cabanas, Ricardo, Saurez, Giselle, Rios, Martha, Alert, José, Reyes, Adnolys, Valdes, Jose, Gonzalez, Maria C., Pedrayes, Jorge L., Avila, Melba, Herrera, Raiza, Infante, Mariela, Echevarria, Ernesto, Moreno, Myrna, Luaces, Patricia Lorenzo, Ramos, Tania Crombet
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Sprache:eng
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