The Concise Guide to PHARMACOLOGY 2013/14: G Protein‐Coupled Receptors
The Concise Guide to PHARMACOLOGY 2013/14 provides concise overviews of the key properties of over 2000 human drug targets with their pharmacology, plus links to an open access knowledgebase of drug targets and their ligands (www.guidetopharmacology.org), which provides more detailed views of target...
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Veröffentlicht in: | British journal of pharmacology 2013-12, Vol.170 (8), p.1459-1581 |
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container_title | British journal of pharmacology |
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creator | Alexander, Stephen P.H. Benson, Helen E. Faccenda, Elena Pawson, Adam J. Sharman, Joanna L. Spedding, Michael Peters, John A. Harmar, Anthony J. |
description | The Concise Guide to PHARMACOLOGY 2013/14 provides concise overviews of the key properties of over 2000 human drug targets with their pharmacology, plus links to an open access knowledgebase of drug targets and their ligands (www.guidetopharmacology.org), which provides more detailed views of target and ligand properties. The full contents can be found at http://onlinelibrary.wiley.com/doi/10.1111/bph.12444/full.
G protein‐coupled receptors are one of the seven major pharmacological targets into which the Guide is divided, with the others being G protein‐coupled receptors, ligand‐gated ion channels, ion channels, catalytic receptors, nuclear hormone receptors, transporters and enzymes. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. A new landscape format has easy to use tables comparing related targets.
It is a condensed version of material contemporary to late 2013, which is presented in greater detail and constantly updated on the website www.guidetopharmacology.org, superseding data presented in previous Guides to Receptors and Channels. It is produced in conjunction with NC‐IUPHAR and provides the official IUPHAR classification and nomenclature for human drug targets, where appropriate. It consolidates information previously curated and displayed separately in IUPHAR‐DB and the Guide to Receptors and Channels, providing a permanent, citable, point‐in‐time record that will survive database updates. |
doi_str_mv | 10.1111/bph.12445 |
format | Article |
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G protein‐coupled receptors are one of the seven major pharmacological targets into which the Guide is divided, with the others being G protein‐coupled receptors, ligand‐gated ion channels, ion channels, catalytic receptors, nuclear hormone receptors, transporters and enzymes. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. A new landscape format has easy to use tables comparing related targets.
It is a condensed version of material contemporary to late 2013, which is presented in greater detail and constantly updated on the website www.guidetopharmacology.org, superseding data presented in previous Guides to Receptors and Channels. It is produced in conjunction with NC‐IUPHAR and provides the official IUPHAR classification and nomenclature for human drug targets, where appropriate. It consolidates information previously curated and displayed separately in IUPHAR‐DB and the Guide to Receptors and Channels, providing a permanent, citable, point‐in‐time record that will survive database updates.</description><identifier>ISSN: 0007-1188</identifier><identifier>ISSN: 1476-5381</identifier><identifier>EISSN: 1476-5381</identifier><identifier>DOI: 10.1111/bph.12445</identifier><identifier>PMID: 24517644</identifier><language>eng</language><publisher>England: Blackwell Publishing Ltd</publisher><subject>Databases, Pharmaceutical ; Humans ; Ligands ; Molecular Targeted Therapy ; Pharmaceutical Preparations - chemistry ; Pharmacology ; Proteins ; Receptors, G-Protein-Coupled - metabolism</subject><ispartof>British journal of pharmacology, 2013-12, Vol.170 (8), p.1459-1581</ispartof><rights>2013 The Authors. British Journal of Pharmacology published by John Wiley & Sons Ltd on behalf of The British Pharmacological Society.</rights><rights>Copyright © 2013 The British Pharmacological Society.</rights><rights>Copyright © 2013 The British Pharmacological Society</rights><rights>Copyright © 2013 The British Pharmacological Society 2013</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c5095-8adbccc440873c92e4db3bc4aefd840dc942b23333f258a0f6d8aa0fea4f1fed3</citedby><cites>FETCH-LOGICAL-c5095-8adbccc440873c92e4db3bc4aefd840dc942b23333f258a0f6d8aa0fea4f1fed3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3892287/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3892287/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,881,1411,1427,27901,27902,45550,45551,46384,46808,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24517644$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Alexander, Stephen P.H.</creatorcontrib><creatorcontrib>Benson, Helen E.</creatorcontrib><creatorcontrib>Faccenda, Elena</creatorcontrib><creatorcontrib>Pawson, Adam J.</creatorcontrib><creatorcontrib>Sharman, Joanna L.</creatorcontrib><creatorcontrib>Spedding, Michael</creatorcontrib><creatorcontrib>Peters, John A.</creatorcontrib><creatorcontrib>Harmar, Anthony J.</creatorcontrib><creatorcontrib>CGTP Collaborators</creatorcontrib><title>The Concise Guide to PHARMACOLOGY 2013/14: G Protein‐Coupled Receptors</title><title>British journal of pharmacology</title><addtitle>Br J Pharmacol</addtitle><description>The Concise Guide to PHARMACOLOGY 2013/14 provides concise overviews of the key properties of over 2000 human drug targets with their pharmacology, plus links to an open access knowledgebase of drug targets and their ligands (www.guidetopharmacology.org), which provides more detailed views of target and ligand properties. The full contents can be found at http://onlinelibrary.wiley.com/doi/10.1111/bph.12444/full.
G protein‐coupled receptors are one of the seven major pharmacological targets into which the Guide is divided, with the others being G protein‐coupled receptors, ligand‐gated ion channels, ion channels, catalytic receptors, nuclear hormone receptors, transporters and enzymes. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. A new landscape format has easy to use tables comparing related targets.
It is a condensed version of material contemporary to late 2013, which is presented in greater detail and constantly updated on the website www.guidetopharmacology.org, superseding data presented in previous Guides to Receptors and Channels. It is produced in conjunction with NC‐IUPHAR and provides the official IUPHAR classification and nomenclature for human drug targets, where appropriate. It consolidates information previously curated and displayed separately in IUPHAR‐DB and the Guide to Receptors and Channels, providing a permanent, citable, point‐in‐time record that will survive database updates.</description><subject>Databases, Pharmaceutical</subject><subject>Humans</subject><subject>Ligands</subject><subject>Molecular Targeted Therapy</subject><subject>Pharmaceutical Preparations - chemistry</subject><subject>Pharmacology</subject><subject>Proteins</subject><subject>Receptors, G-Protein-Coupled - metabolism</subject><issn>0007-1188</issn><issn>1476-5381</issn><issn>1476-5381</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>24P</sourceid><sourceid>EIF</sourceid><recordid>eNp1kcFO3DAQhi0EKtttD30BFIkLPYS1HXvjcEDaRmUXaRErRA-cLMeesEHZONhJK259hD4jT4KXXVBBYi5zmE_fzOhH6BvBxyTUqGiXx4QyxnfQgLB0HPNEkF00wBinMSFC7KPP3t9hHIYp_4T2KeMkHTM2QLPrJUS5bXTlIZr2lYGos9FiNrm6mOSX88vpTUQxSUaEnUTTaOFsB1Xz-Pdfbvu2BhNdgYa2s85_QXulqj183fYh-nX28zqfxcFxnk_mseY447FQptBaM4ZFmuiMAjNFUmimoDSCYaMzRguahCopFwqXYyNUaKBYSUowyRCdbrxtX6zAaGg6p2rZumql3IO0qpJvJ021lLf2t0xERmlYOkRHW4Gz9z34Tq4qr6GuVQO295KwLCOMpxwH9PAdemd714T3JOFUjNcfranvG0o7672D8vUYguU6Hxnykc_5BPbg_-tfyZdAAjDaAH-qGh4-Nskfi9lG-QTM9Jil</recordid><startdate>201312</startdate><enddate>201312</enddate><creator>Alexander, Stephen P.H.</creator><creator>Benson, Helen E.</creator><creator>Faccenda, Elena</creator><creator>Pawson, Adam J.</creator><creator>Sharman, Joanna L.</creator><creator>Spedding, Michael</creator><creator>Peters, John A.</creator><creator>Harmar, Anthony J.</creator><general>Blackwell Publishing Ltd</general><general>John Wiley & Sons, Ltd</general><scope>24P</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QP</scope><scope>7TK</scope><scope>K9.</scope><scope>NAPCQ</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>201312</creationdate><title>The Concise Guide to PHARMACOLOGY 2013/14: G Protein‐Coupled Receptors</title><author>Alexander, Stephen P.H. ; 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The full contents can be found at http://onlinelibrary.wiley.com/doi/10.1111/bph.12444/full.
G protein‐coupled receptors are one of the seven major pharmacological targets into which the Guide is divided, with the others being G protein‐coupled receptors, ligand‐gated ion channels, ion channels, catalytic receptors, nuclear hormone receptors, transporters and enzymes. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. A new landscape format has easy to use tables comparing related targets.
It is a condensed version of material contemporary to late 2013, which is presented in greater detail and constantly updated on the website www.guidetopharmacology.org, superseding data presented in previous Guides to Receptors and Channels. It is produced in conjunction with NC‐IUPHAR and provides the official IUPHAR classification and nomenclature for human drug targets, where appropriate. It consolidates information previously curated and displayed separately in IUPHAR‐DB and the Guide to Receptors and Channels, providing a permanent, citable, point‐in‐time record that will survive database updates.</abstract><cop>England</cop><pub>Blackwell Publishing Ltd</pub><pmid>24517644</pmid><doi>10.1111/bph.12445</doi><tpages>0</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Databases, Pharmaceutical Humans Ligands Molecular Targeted Therapy Pharmaceutical Preparations - chemistry Pharmacology Proteins Receptors, G-Protein-Coupled - metabolism |
title | The Concise Guide to PHARMACOLOGY 2013/14: G Protein‐Coupled Receptors |
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