Ferulate-5-hydroxylase from Arabidopsis thaliana defines a new family of cytochrome P450-dependent monooxygenases

The fah1 mutant of Arabidopsis is defective in the accumulation of sinapic acid-derived metabolites, including the guaiacyl-syringyl lignin typical of angiosperms. Earlier results indicated that the FAH1 locus encodes ferulate-5-hydroxylase (FSH), a cytochrome P450-dependent monooxygenase (P450) of...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 1996-07, Vol.93 (14), p.6869-6874
Hauptverfasser:	Meyer, K. (Purdue University, West Lafayette, IN.), Cusumano, J.C, Somerville, C, Chapple, C.C.S
Format:	Artikel
Sprache:	eng
Schlagworte:	ADN Alleles Amino Acid Sequence Amino acids Arabidopsis - enzymology Arabidopsis - genetics Arabidopsis Proteins ARABIDOPSIS THALIANA Biochemistry Blotting, Southern CITOCROMO P 450 CITOCROMOS CLONACION CLONAGE Cloning, Molecular Complementary DNA COMPOSICION QUIMICA COMPOSITION CHIMIQUE Cosmids CYTOCHROME CYTOCHROME P 450 Cytochrome P-450 Enzyme System - chemistry Cytochrome P-450 Enzyme System - genetics Cytochrome P-450 Enzyme System - metabolism Cytochromes Deoxyribonucleic acid DNA DNA, Bacterial - metabolism DNA, Single-Stranded - metabolism Enzymes GENE GENES Genes, Plant Genomics Lignin METABOLITE Metabolites METABOLITOS Mixed Function Oxygenases - chemistry Mixed Function Oxygenases - genetics Mixed Function Oxygenases - metabolism Molecular Sequence Data Multigene Family MUTACION MUTANT MUTANTES MUTATION OXIDORREDUCTASAS OXYDOREDUCTASE Phylogeny PLANTAS TRANSGENICAS PLANTE TRANSGENIQUE Plasmids SECUENCIA NUCLEOTIDICA Sequence Homology, Amino Acid SEQUENCE NUCLEOTIDIQUE
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