Serum metabolomic profile and potential biomarkers for severity of fibrosis in nonalcoholic fatty liver disease

Background Biomarker for usefulness in diagnosing advanced fibrosis in nonalcoholic fatty liver disease (NAFLD) is expected. In order to discover novel biomarkers for NAFLD and its pathogenesis, we performed matabolomics screening. Methods (1) The initial cohort was 44 NAFLD patients. (2) This valid...

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Veröffentlicht in:	Journal of gastroenterology 2013-12, Vol.48 (12), p.1392-1400
Hauptverfasser:	Tokushige, Katsutoshi, Hashimoto, Etsuko, Kodama, Kazuhisa, Tobari, Maki, Matsushita, Noriko, Kogiso, Tomomi, Taniai, Makiko, Torii, Nobuyuki, Shiratori, Keiko, Nishizaki, Yasuhiro, Ohga, Takushi, Ohashi, Yoshiaki, Sato, Takaya
Format:	Artikel
Sprache:	eng
Schlagworte:	Abdominal Surgery Adult Aged Aged, 80 and over Biliary Tract Biological markers Biomarkers - metabolism Case-Control Studies Chromatography, Liquid - methods Cohort Studies Colorectal Surgery Dehydroepiandrosterone Disease Progression Electrophoresis, Capillary - methods Fatty liver Fatty Liver - diagnosis Fatty Liver - metabolism Fatty Liver - physiopathology Female Fibrosis Gastroenterology Hepatology Hormones, Sex Humans Liquid chromatography Liver cirrhosis Liver Cirrhosis - diagnosis Liver Cirrhosis - metabolism Liver Cirrhosis - physiopathology Liver Cirrhosis, Biliary - diagnosis Liver Cirrhosis, Biliary - metabolism Liver Cirrhosis, Biliary - physiopathology Male Mass spectrometry Mass Spectrometry - methods Medicine Medicine & Public Health Metabolites Metabolomics - methods Middle Aged Non-alcoholic Fatty Liver Disease Original Article—Liver Original —Liver, Pancreas, and Biliary Tract Pancreas Severity of Illness Index Sulfates Surgical Oncology Type 2 diabetes
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