Maintenance of biologic-free remission with naproxen or no treatment in patients with early, active axial spondyloarthritis: results from a 6-month, randomised, open-label follow-up study, INFAST Part 2

Objective To investigate whether biologic-free remission can be achieved in patients with early, active axial spondyloarthritis (SpA) who were in partial remission after 28 weeks of infliximab (IFX)+naproxen (NPX) or placebo (PBO)+NPX treatment and whether treatment with NPX was superior to no treat...

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Veröffentlicht in:	Annals of the rheumatic diseases 2014-01, Vol.73 (1), p.108-113
Hauptverfasser:	Sieper, J, Lenaerts, J, Wollenhaupt, J, Rudwaleit, M, Mazurov, V I, Myasoutova, L, Park, S, Song, Y, Yao, R, Chitkara, D, Vastesaeger, N
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Anti-Inflammatory Agents, Non-Steroidal - administration & dosage Anti-Inflammatory Agents, Non-Steroidal - adverse effects Clinical and Epidemiological Research Double-Blind Method Early Diagnosis Female Follow-Up Studies Humans Male Middle Aged Naproxen - administration & dosage Naproxen - adverse effects Nonsteroidal anti-inflammatory drugs Placebos Quality of life Remission Induction Spondylarthritis - diagnosis Spondylarthritis - drug therapy Spondylitis, Ankylosing - diagnosis Spondylitis, Ankylosing - drug therapy Studies Treatment Outcome Tumor necrosis factor-TNF Young Adult
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