Rrp47 functions in RNA surveillance and stable RNA processing when divorced from the exoribonuclease and exosome-binding domains of Rrp6

The eukaryotic exosome exoribonuclease Rrp6 forms a complex with Rrp47 that functions in nuclear RNA quality control mechanisms, the degradation of cryptic unstable transcripts (CUTs), and in the 3' end maturation of stable RNAs. Stable expression of Rrp47 is dependent upon its interaction with...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	RNA (Cambridge) 2013-12, Vol.19 (12), p.1659-1668
Hauptverfasser:	Garland, William, Feigenbutz, Monika, Turner, Martin, Mitchell, Phil
Format:	Artikel
Sprache:	eng
Schlagworte:	Binding, Competitive Catalytic Domain DNA-Binding Proteins - chemistry DNA-Binding Proteins - physiology Exoribonucleases - genetics Exoribonucleases - metabolism Exosome Multienzyme Ribonuclease Complex - chemistry Exosome Multienzyme Ribonuclease Complex - genetics Exosome Multienzyme Ribonuclease Complex - metabolism Exosome Multienzyme Ribonuclease Complex - physiology Gene Expression Nuclear Proteins - chemistry Nuclear Proteins - physiology Protein Binding Protein Interaction Domains and Motifs RNA Processing, Post-Transcriptional RNA Stability RNA, Fungal - metabolism RNA-Binding Proteins - chemistry RNA-Binding Proteins - genetics RNA-Binding Proteins - metabolism RNA-Binding Proteins - physiology Saccharomyces cerevisiae - enzymology Saccharomyces cerevisiae - genetics Saccharomyces cerevisiae - growth & development Saccharomyces cerevisiae Proteins - chemistry Saccharomyces cerevisiae Proteins - genetics Saccharomyces cerevisiae Proteins - metabolism Saccharomyces cerevisiae Proteins - physiology Sequence Deletion
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!