Role of ceruloplasmin in nitric oxide metabolism in plasma of humans and sheep: a comparison of adults and fetuses

Nitric oxide (NO) is metabolized in plasma, in part by the ferroxidase ceruloplasmin (Cp), to form nitrite and nitrosothiols (SNOs), which are proposed to mediate protective responses to hypoxia and ischemia. We hypothesized that NO metabolism would be attenuated in fetal plasma due to low Cp activi...

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Veröffentlicht in:	American journal of physiology. Regulatory, integrative and comparative physiology integrative and comparative physiology, 2013-12, Vol.305 (11), p.R1401-R1410
Hauptverfasser:	Vrancken, Kurt, Schroeder, Hobe J, Longo, Lawrence D, Power, Gordon G, Blood, Arlin B
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aging Animals Cardiovascular and Renal Integration Ceruloplasmin - metabolism Fetus Half-Life Humans Nitric Oxide - metabolism Oxidation-Reduction S-Nitrosothiols - metabolism Sheep
Online-Zugang:	Volltext
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