Gastric inhibitory polypeptide receptor (GIPR) is a promising target for imaging and therapy in neuroendocrine tumors

Background Ligands binding the somatostatin receptor type 2 (SSTR2) are useful for imaging and treatment of neuroendocrine tumors (NETs), but not all tumors express high levels of these receptors. The aim of this study was to evaluate gene expression of new therapeutic targets in NETs relative to SS...

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Veröffentlicht in:	Surgery 2013-12, Vol.154 (6), p.1206-1214
Hauptverfasser:	Sherman, Scott K., MD, Carr, Jennifer C., MD, Wang, Donghong, MS, O’Dorisio, M. Sue, MD, PhD, O’Dorisio, Thomas M., MD, Howe, James R., MD
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomarkers, Tumor - genetics Gene Expression Humans Intestinal Neoplasms - diagnosis Intestinal Neoplasms - genetics Intestinal Neoplasms - therapy Ligands Neuroendocrine Tumors - diagnosis Neuroendocrine Tumors - genetics Neuroendocrine Tumors - therapy Neuroimaging Pancreatic Neoplasms - diagnosis Pancreatic Neoplasms - genetics Pancreatic Neoplasms - therapy Receptors, Bombesin - genetics Receptors, G-Protein-Coupled - genetics Receptors, Gastrointestinal Hormone - genetics Receptors, Metabotropic Glutamate - genetics Receptors, Opioid, kappa - genetics Receptors, Oxytocin - genetics Receptors, Somatostatin - genetics RNA, Neoplasm - genetics Surgery
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