Natural antibody response to Plasmodium falciparum merozoite antigens MSP5, MSP9 and EBA175 is associated to clinical protection in the Brazilian Amazon

Antibodies have an essential role in the acquired immune response against blood stage P. falciparum infection. Although several antigens have been identified as important antibody targets, it is still elusive which antigens have to be recognized for clinical protection. Herein, we analyzed antibodie...

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Veröffentlicht in:	BMC infectious diseases 2013-12, Vol.13 (1), p.608-608, Article 608
Hauptverfasser:	Medeiros, Márcia M, Fotoran, Wesley L, dalla Martha, Rosimeire C, Katsuragawa, Tony H, Pereira da Silva, Luiz Hildebrando, Wunderlich, Gerhard
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies Antibodies, Protozoan - blood Antibodies, Protozoan - immunology Antigen-antibody reactions Antigens Antigens, Protozoan - blood Antigens, Protozoan - immunology Blood Brazil Care and treatment Cross Protection Enzyme-Linked Immunosorbent Assay Erythrocytes Female Health aspects Humans Immune response Immunoglobulin G Ligands Malaria Malaria, Falciparum - blood Malaria, Falciparum - immunology Malaria, Falciparum - parasitology Malaria, Falciparum - prevention & control Male Membrane Proteins - blood Membrane Proteins - immunology Middle Aged Mortality Parasites Plasmodium falciparum Plasmodium falciparum - genetics Plasmodium falciparum - immunology Plasmodium falciparum - isolation & purification Proteins Protozoan Proteins - blood Protozoan Proteins - immunology Risk factors Vaccines Viral antibodies
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