Pharmacokinetics of Mirabegron, a β3-Adrenoceptor Agonist for Treatment of Overactive Bladder, in Healthy Japanese Male Subjects: Results from Single- and Multiple-Dose Studies

Background Mirabegron is a human β 3 -adrenoceptor agonist for the treatment of overactive bladder. The pharmacokinetic profile of mirabegron has been extensively characterized in healthy Caucasian subjects. Objective The objective of this study was to evaluate the pharmacokinetics, dose-proportiona...

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Veröffentlicht in:Clinical drug investigation 2014, Vol.34 (1), p.27-35
Hauptverfasser: Iitsuka, Hiromi, Tokuno, Tomoaki, Amada, Yoko, Matsushima, Hiroshi, Katashima, Masataka, Sawamoto, Taiji, Takusagawa, Shin, van Gelderen, Marcel, Tanaka, Takanori, Miyahara, Hideo
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Sprache:eng
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