Does the revised cardiac risk index predict cardiac complications following elective lung resection?
Revised Cardiac Risk Index (RCRI) score and Thoracic Revised Cardiac Risk Index (ThRCRI) score were developed to predict the risks of postoperative major cardiac complications in generic surgical population and thoracic surgery respectively. This study aims to determine the accuracy of these scores...
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Veröffentlicht in: | Journal of cardiothoracic surgery 2013-12, Vol.8 (1), p.220-220, Article 220 |
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creator | Wotton, Robin Marshall, Andrea Kerr, Amy Bishay, Ehab Kalkat, Maninder Rajesh, Pala Steyn, Richard Naidu, Babu Abdelaziz, Mahmoud Hussain, Khalid |
description | Revised Cardiac Risk Index (RCRI) score and Thoracic Revised Cardiac Risk Index (ThRCRI) score were developed to predict the risks of postoperative major cardiac complications in generic surgical population and thoracic surgery respectively. This study aims to determine the accuracy of these scores in predicting the risk of developing cardiac complications including atrial arrhythmias after lung resection surgery in adults.
We studied 703 patients undergoing lung resection surgery in a tertiary thoracic surgery centre. Observed outcome measures of postoperative cardiac morbidity and mortality were compared against those predicted by risk.
Postoperative major cardiac complications and supraventricular arrhythmias occurred in 4.8% of patients. Both index scores had poor discriminative ability for predicting postoperative cardiac complications with an area under receiver operating characteristic (ROC) curve of 0.59 (95% CI 0.51-0.67) for the RCRI score and 0.57 (95% CI 0.49-0.66) for the ThRCRI score.
In our cohort, RCRI and ThRCRI scores failed to accurately predict the risk of cardiac complications in patients undergoing elective resection of lung cancer. The British Thoracic Society (BTS) recommendation to seek a cardiology referral for all asymptomatic pre-operative lung resection patients with > 3 RCRI risk factors is thus unlikely to be of clinical benefit. |
doi_str_mv | 10.1186/1749-8090-8-220 |
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We studied 703 patients undergoing lung resection surgery in a tertiary thoracic surgery centre. Observed outcome measures of postoperative cardiac morbidity and mortality were compared against those predicted by risk.
Postoperative major cardiac complications and supraventricular arrhythmias occurred in 4.8% of patients. Both index scores had poor discriminative ability for predicting postoperative cardiac complications with an area under receiver operating characteristic (ROC) curve of 0.59 (95% CI 0.51-0.67) for the RCRI score and 0.57 (95% CI 0.49-0.66) for the ThRCRI score.
In our cohort, RCRI and ThRCRI scores failed to accurately predict the risk of cardiac complications in patients undergoing elective resection of lung cancer. The British Thoracic Society (BTS) recommendation to seek a cardiology referral for all asymptomatic pre-operative lung resection patients with > 3 RCRI risk factors is thus unlikely to be of clinical benefit.</description><identifier>ISSN: 1749-8090</identifier><identifier>EISSN: 1749-8090</identifier><identifier>DOI: 10.1186/1749-8090-8-220</identifier><identifier>PMID: 24289748</identifier><language>eng</language><publisher>England: BioMed Central Ltd</publisher><subject>Aged ; Arrhythmia ; Arrhythmias, Cardiac - epidemiology ; Cardiac arrhythmia ; Cardiac patients ; Cardiovascular disease ; Chronic obstructive pulmonary disease ; Complications and side effects ; Confidence intervals ; Female ; Health aspects ; Heart ; Heart attacks ; Heart failure ; Hospitals ; Humans ; Intensive care ; Logistic Models ; Lung cancer ; Lung Neoplasms - surgery ; Male ; Medical research ; Medicine, Experimental ; Middle Aged ; Mortality ; Multivariate analysis ; Ostomy ; Pneumonectomy - adverse effects ; Pneumonectomy - statistics & numerical data ; Postoperative Complications - epidemiology ; Prognosis ; Prospective Studies ; Risk assessment ; Risk Factors ; ROC Curve ; Statistical methods ; Studies ; Surgery ; Thoracic surgery ; Variables</subject><ispartof>Journal of cardiothoracic surgery, 2013-12, Vol.8 (1), p.220-220, Article 220</ispartof><rights>COPYRIGHT 2013 BioMed Central Ltd.</rights><rights>2013 Wotton et al.; licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</rights><rights>Copyright © 2013 Wotton et al.; licensee BioMed Central Ltd. 2013 Wotton et al.; licensee BioMed Central Ltd.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-b613t-5558c7761ef514be1dc8057e3a68e9e42275fa5da865e690f48fa7fd2707791b3</citedby><cites>FETCH-LOGICAL-b613t-5558c7761ef514be1dc8057e3a68e9e42275fa5da865e690f48fa7fd2707791b3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3879030/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3879030/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,860,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24289748$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Wotton, Robin</creatorcontrib><creatorcontrib>Marshall, Andrea</creatorcontrib><creatorcontrib>Kerr, Amy</creatorcontrib><creatorcontrib>Bishay, Ehab</creatorcontrib><creatorcontrib>Kalkat, Maninder</creatorcontrib><creatorcontrib>Rajesh, Pala</creatorcontrib><creatorcontrib>Steyn, Richard</creatorcontrib><creatorcontrib>Naidu, Babu</creatorcontrib><creatorcontrib>Abdelaziz, Mahmoud</creatorcontrib><creatorcontrib>Hussain, Khalid</creatorcontrib><title>Does the revised cardiac risk index predict cardiac complications following elective lung resection?</title><title>Journal of cardiothoracic surgery</title><addtitle>J Cardiothorac Surg</addtitle><description>Revised Cardiac Risk Index (RCRI) score and Thoracic Revised Cardiac Risk Index (ThRCRI) score were developed to predict the risks of postoperative major cardiac complications in generic surgical population and thoracic surgery respectively. This study aims to determine the accuracy of these scores in predicting the risk of developing cardiac complications including atrial arrhythmias after lung resection surgery in adults.
We studied 703 patients undergoing lung resection surgery in a tertiary thoracic surgery centre. Observed outcome measures of postoperative cardiac morbidity and mortality were compared against those predicted by risk.
Postoperative major cardiac complications and supraventricular arrhythmias occurred in 4.8% of patients. Both index scores had poor discriminative ability for predicting postoperative cardiac complications with an area under receiver operating characteristic (ROC) curve of 0.59 (95% CI 0.51-0.67) for the RCRI score and 0.57 (95% CI 0.49-0.66) for the ThRCRI score.
In our cohort, RCRI and ThRCRI scores failed to accurately predict the risk of cardiac complications in patients undergoing elective resection of lung cancer. The British Thoracic Society (BTS) recommendation to seek a cardiology referral for all asymptomatic pre-operative lung resection patients with > 3 RCRI risk factors is thus unlikely to be of clinical benefit.</description><subject>Aged</subject><subject>Arrhythmia</subject><subject>Arrhythmias, Cardiac - epidemiology</subject><subject>Cardiac arrhythmia</subject><subject>Cardiac patients</subject><subject>Cardiovascular disease</subject><subject>Chronic obstructive pulmonary disease</subject><subject>Complications and side effects</subject><subject>Confidence intervals</subject><subject>Female</subject><subject>Health aspects</subject><subject>Heart</subject><subject>Heart attacks</subject><subject>Heart failure</subject><subject>Hospitals</subject><subject>Humans</subject><subject>Intensive care</subject><subject>Logistic Models</subject><subject>Lung cancer</subject><subject>Lung Neoplasms - surgery</subject><subject>Male</subject><subject>Medical research</subject><subject>Medicine, Experimental</subject><subject>Middle Aged</subject><subject>Mortality</subject><subject>Multivariate analysis</subject><subject>Ostomy</subject><subject>Pneumonectomy - adverse effects</subject><subject>Pneumonectomy - statistics & numerical data</subject><subject>Postoperative Complications - epidemiology</subject><subject>Prognosis</subject><subject>Prospective Studies</subject><subject>Risk assessment</subject><subject>Risk Factors</subject><subject>ROC Curve</subject><subject>Statistical methods</subject><subject>Studies</subject><subject>Surgery</subject><subject>Thoracic surgery</subject><subject>Variables</subject><issn>1749-8090</issn><issn>1749-8090</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNp1Uk1vFSEUnRgbW6trd2YSN26mBQYGZqNp61eTJt3omjBweaUy8ISZp_57mbz67DNtWMC995wD93Cr6hVGJxiL7hRz2jcC9agRDSHoSXW0yzy9dz6snud8ixBlLWLPqkNCieg5FUeV-RAh19MN1Ak2LoOptUrGKV0nl7_XLhj4Va8TGKenXUnHce2dVpOLIdc2eh9_urCqwYOe3AZqP5coQV7CGN6_qA6s8hle3u3H1bdPH79efGmurj9fXpxdNUOH26lhjAnNeYfBMkwHwEYLxDi0qhPQAyWEM6uYUaJj0PXIUmEVt4ZwxHmPh_a4erfVXc_DCEZDmJLycp3cqNJvGZWT-5XgbuQqbmQreI9aVATOtwKDi48I7FeKE3JxWS4uSyHLHxSRt3evSPHHDHmSo8savFcB4pwlpj3ihBVagb75D3ob5xSKRwXFEROk5eQfaqU8SBdsLHfrRVSesZZyLDhdUCcPoMoyMDodA1hX8nuE0y1Bp5hzArvrEyO5TNcDnb2-7-8O_3ec2j9IMsrH</recordid><startdate>20131201</startdate><enddate>20131201</enddate><creator>Wotton, Robin</creator><creator>Marshall, Andrea</creator><creator>Kerr, Amy</creator><creator>Bishay, Ehab</creator><creator>Kalkat, Maninder</creator><creator>Rajesh, Pala</creator><creator>Steyn, Richard</creator><creator>Naidu, Babu</creator><creator>Abdelaziz, Mahmoud</creator><creator>Hussain, Khalid</creator><general>BioMed Central Ltd</general><general>BioMed Central</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FD</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>M7Z</scope><scope>P64</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20131201</creationdate><title>Does the revised cardiac risk index predict cardiac complications following elective lung resection?</title><author>Wotton, Robin ; Marshall, Andrea ; Kerr, Amy ; Bishay, Ehab ; Kalkat, Maninder ; Rajesh, Pala ; Steyn, Richard ; Naidu, Babu ; Abdelaziz, Mahmoud ; Hussain, Khalid</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-b613t-5558c7761ef514be1dc8057e3a68e9e42275fa5da865e690f48fa7fd2707791b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>Aged</topic><topic>Arrhythmia</topic><topic>Arrhythmias, Cardiac - epidemiology</topic><topic>Cardiac arrhythmia</topic><topic>Cardiac patients</topic><topic>Cardiovascular disease</topic><topic>Chronic obstructive pulmonary disease</topic><topic>Complications and side effects</topic><topic>Confidence intervals</topic><topic>Female</topic><topic>Health aspects</topic><topic>Heart</topic><topic>Heart attacks</topic><topic>Heart failure</topic><topic>Hospitals</topic><topic>Humans</topic><topic>Intensive care</topic><topic>Logistic Models</topic><topic>Lung cancer</topic><topic>Lung Neoplasms - surgery</topic><topic>Male</topic><topic>Medical research</topic><topic>Medicine, Experimental</topic><topic>Middle Aged</topic><topic>Mortality</topic><topic>Multivariate analysis</topic><topic>Ostomy</topic><topic>Pneumonectomy - adverse effects</topic><topic>Pneumonectomy - statistics & numerical data</topic><topic>Postoperative Complications - epidemiology</topic><topic>Prognosis</topic><topic>Prospective Studies</topic><topic>Risk assessment</topic><topic>Risk Factors</topic><topic>ROC Curve</topic><topic>Statistical methods</topic><topic>Studies</topic><topic>Surgery</topic><topic>Thoracic surgery</topic><topic>Variables</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Wotton, Robin</creatorcontrib><creatorcontrib>Marshall, Andrea</creatorcontrib><creatorcontrib>Kerr, Amy</creatorcontrib><creatorcontrib>Bishay, Ehab</creatorcontrib><creatorcontrib>Kalkat, Maninder</creatorcontrib><creatorcontrib>Rajesh, Pala</creatorcontrib><creatorcontrib>Steyn, Richard</creatorcontrib><creatorcontrib>Naidu, Babu</creatorcontrib><creatorcontrib>Abdelaziz, Mahmoud</creatorcontrib><creatorcontrib>Hussain, Khalid</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Technology Research Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Biochemistry Abstracts 1</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Journal of cardiothoracic surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Wotton, Robin</au><au>Marshall, Andrea</au><au>Kerr, Amy</au><au>Bishay, Ehab</au><au>Kalkat, Maninder</au><au>Rajesh, Pala</au><au>Steyn, Richard</au><au>Naidu, Babu</au><au>Abdelaziz, Mahmoud</au><au>Hussain, Khalid</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Does the revised cardiac risk index predict cardiac complications following elective lung resection?</atitle><jtitle>Journal of cardiothoracic surgery</jtitle><addtitle>J Cardiothorac Surg</addtitle><date>2013-12-01</date><risdate>2013</risdate><volume>8</volume><issue>1</issue><spage>220</spage><epage>220</epage><pages>220-220</pages><artnum>220</artnum><issn>1749-8090</issn><eissn>1749-8090</eissn><abstract>Revised Cardiac Risk Index (RCRI) score and Thoracic Revised Cardiac Risk Index (ThRCRI) score were developed to predict the risks of postoperative major cardiac complications in generic surgical population and thoracic surgery respectively. This study aims to determine the accuracy of these scores in predicting the risk of developing cardiac complications including atrial arrhythmias after lung resection surgery in adults.
We studied 703 patients undergoing lung resection surgery in a tertiary thoracic surgery centre. Observed outcome measures of postoperative cardiac morbidity and mortality were compared against those predicted by risk.
Postoperative major cardiac complications and supraventricular arrhythmias occurred in 4.8% of patients. Both index scores had poor discriminative ability for predicting postoperative cardiac complications with an area under receiver operating characteristic (ROC) curve of 0.59 (95% CI 0.51-0.67) for the RCRI score and 0.57 (95% CI 0.49-0.66) for the ThRCRI score.
In our cohort, RCRI and ThRCRI scores failed to accurately predict the risk of cardiac complications in patients undergoing elective resection of lung cancer. The British Thoracic Society (BTS) recommendation to seek a cardiology referral for all asymptomatic pre-operative lung resection patients with > 3 RCRI risk factors is thus unlikely to be of clinical benefit.</abstract><cop>England</cop><pub>BioMed Central Ltd</pub><pmid>24289748</pmid><doi>10.1186/1749-8090-8-220</doi><tpages>1</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Aged Arrhythmia Arrhythmias, Cardiac - epidemiology Cardiac arrhythmia Cardiac patients Cardiovascular disease Chronic obstructive pulmonary disease Complications and side effects Confidence intervals Female Health aspects Heart Heart attacks Heart failure Hospitals Humans Intensive care Logistic Models Lung cancer Lung Neoplasms - surgery Male Medical research Medicine, Experimental Middle Aged Mortality Multivariate analysis Ostomy Pneumonectomy - adverse effects Pneumonectomy - statistics & numerical data Postoperative Complications - epidemiology Prognosis Prospective Studies Risk assessment Risk Factors ROC Curve Statistical methods Studies Surgery Thoracic surgery Variables |
title | Does the revised cardiac risk index predict cardiac complications following elective lung resection? |
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