Inferring the choreography of parental genomes during fertilization from ultralarge-scale whole-transcriptome analysis

Fertilization precisely choreographs parental genomes by using gamete-derived cellular factors and activating genome regulatory programs. However, the mechanism remains elusive owing to the technical difficulties of preparing large numbers of high-quality preimplantation cells. Here, we collected &g...

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Veröffentlicht in:	Genes & development 2013-12, Vol.27 (24), p.2736-2748
Hauptverfasser:	Park, Sung-Joon, Komata, Makiko, Inoue, Fukashi, Yamada, Kaori, Nakai, Kenta, Ohsugi, Miho, Shirahige, Katsuhiko
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cluster Analysis Databases, Genetic Female Fertilization - genetics Gene Expression Profiling Gene Expression Regulation, Developmental Gene Regulatory Networks Male Mice Oocytes - physiology Promoter Regions, Genetic Protein Interaction Domains and Motifs Resource/Methodology RNA, Messenger - metabolism Spermatozoa - physiology Time Factors Transcription Factors - genetics Transcriptome
Online-Zugang:	Volltext
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