TAp63 regulates oncogenic miR-155 to mediate migration and tumour growth

miR-155 is an oncogenic microRNA which is upregulated in many solid cancers. The targets of miR-155 are well established , with over 100 confirmed mRNA targets. However, the regulation of miR-155 and the basis of its upregulation in cancer is not well understood. We have previously shown that miR-15...

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Veröffentlicht in:	Oncotarget 2013-11, Vol.4 (11), p.1894-1903
Hauptverfasser:	Mattiske, Sam, Ho, Kristen, Noll, Jacqueline E, Neilsen, Paul M, Callen, David F, Suetani, Rachel J
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Breast Neoplasms - genetics Breast Neoplasms - metabolism Breast Neoplasms - pathology Cell Movement - physiology Female Gene Expression Regulation, Neoplastic Gene Knockdown Techniques Heterografts Humans Mice Mice, Inbred BALB C Mice, Nude MicroRNAs - antagonists & inhibitors MicroRNAs - biosynthesis MicroRNAs - genetics MicroRNAs - metabolism Research Paper Transcription Factors - biosynthesis Transcription Factors - genetics Transcription Factors - metabolism Tumor Suppressor Proteins - biosynthesis Tumor Suppressor Proteins - genetics Tumor Suppressor Proteins - metabolism Up-Regulation
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