Enhanced Cell Death Imaging Using Multivalent Zinc(II)-bis(dipicolylamine) Fluorescent Probes

There is a clinical need for imaging technologies that can accurately detect cell death in a multitude of pathological conditions. Zinc(II)-bis(dipicolylamine) (Zn2BDPA) coordination complexes are known to associate with the anionic phosphatidylserine that is exposed on the surface of dead and dying...

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Veröffentlicht in:	Molecular pharmaceutics 2013-09, Vol.10 (9), p.3296-3303
Hauptverfasser:	Smith, Bryan A, Harmatys, Kara M, Xiao, Shuzhang, Cole, Erin L, Plaunt, Adam J, Wolter, William, Suckow, Mark A, Smith, Bradley D
Format:	Artikel
Sprache:	eng
Schlagworte:	Amines - chemistry Animals Brain Injuries - pathology Cell Death - physiology Cell Line Diagnostic Imaging - methods Fluorescent Dyes - chemistry Humans Male Mice Picolinic Acids - chemistry Prostatic Neoplasms - pathology Rats Thymus Gland - pathology Zinc - chemistry
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