Expression of core 3 synthase in human pancreatic cancer cells suppresses tumor growth and metastasis

Core 3‐derived glycans, a major type of O‐glycan expressed by normal epithelial cells of the gastrointestinal tract, are downregulated during malignancy because of loss of expression of functional β3‐N‐acetylglucosaminyltransferase‐6 (core 3 synthase). We investigated the expression of core 3 syntha...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	International journal of cancer 2013-12, Vol.133 (12), p.2824-2833
Hauptverfasser:	Radhakrishnan, Prakash, Grandgenett, Paul M., Mohr, Ashley M., Bunt, Stephanie K., Yu, Fang, Chowdhury, Sanjib, Hollingsworth, Michael A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Actins - metabolism Biological and medical sciences Cancer Cell Line, Tumor Cell Proliferation core 3 synthase Focal Adhesion Protein-Tyrosine Kinases - metabolism Gastroenterology. Liver. Pancreas. Abdomen Gene Expression Regulation, Neoplastic Genotype & phenotype Humans Integrin alpha2beta1 - analysis Liver. Biliary tract. Portal circulation. Exocrine pancreas Medical research Medical sciences Metastasis MUC1 Mucin-1 - metabolism Multiple tumors. Solid tumors. Tumors in childhood (general aspects) N-Acetylglucosaminyltransferases - genetics N-Acetylglucosaminyltransferases - metabolism N-Acetylglucosaminyltransferases - physiology Neoplasm Metastasis O‐glycan Pancreatic cancer Pancreatic Neoplasms - pathology Rodents Tumors α2β1 integrin
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!