Peptide vaccination in Montanide adjuvant induces and GM-CSF increases CXCR3 and cutaneous lymphocyte antigen expression by tumor antigen-specific CD8 T cells

T cell infiltration of melanoma is associated with enhanced clinical efficacy and is a desirable endpoint of immunotherapeutic vaccination. Infiltration is regulated, in part, by chemokine receptors and selectin ligands on the surface of tumor-specific lymphocytes. Therefore, we investigated the exp...

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Veröffentlicht in:Cancer immunology research 2013-11, Vol.1 (5), p.332-339
Hauptverfasser: Clancy-Thompson, Eleanor, King, Laura K, Nunnley, Lenora D, Mullins, Irene M, Slingluff, Jr, Craig L, Mullins, David W
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Sprache:eng
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