Effect of Paricalcitol on Left Ventricular Mass and Function in CKD—The OPERA Trial

Vitamin D seems to protect against cardiovascular disease, but the reported effects of vitamin D on patient outcomes in CKD are controversial. We conducted a prospective, double blind, randomized, placebo-controlled trial to determine whether oral activated vitamin D reduces left ventricular (LV) ma...

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Veröffentlicht in:	Journal of the American Society of Nephrology 2014-01, Vol.25 (1), p.175-186
Hauptverfasser:	WANG, Angela Yee-Moon, FANG FANG, YU, Cheuk-Man, CHAN, John, WEN, Yue-Yi, SHANG QING, CHAN, Iris Hiu-Shuen, LO, Gladys, LAI, Kar-Neng, LO, Wai-Kei, LAM, Christopher Wai-Kei
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Alkaline Phosphatase - blood Biological and medical sciences Blood Pressure - drug effects Clinical Research Double-Blind Method Echocardiography Ergocalciferols - adverse effects Ergocalciferols - therapeutic use Female Humans Hypercalcemia - chemically induced Hypertrophy, Left Ventricular - drug therapy Hypertrophy, Left Ventricular - etiology Hypertrophy, Left Ventricular - pathology Kidneys Magnetic Resonance Imaging Male Medical sciences Middle Aged Nephrology. Urinary tract diseases Nephropathies. Renovascular diseases. Renal failure Parathyroid Hormone - blood Prospective Studies Renal failure Renal Insufficiency, Chronic - complications Renal Insufficiency, Chronic - drug therapy Renal Insufficiency, Chronic - pathology Urinary system involvement in other diseases. Miscellaneous Ventricular Dysfunction, Left - drug therapy Ventricular Dysfunction, Left - etiology Ventricular Dysfunction, Left - physiopathology
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