king cobra genome reveals dynamic gene evolution and adaptation in the snake venom system

Snakes are limbless predators, and many species use venom to help overpower relatively large, agile prey. Snake venoms are complex protein mixtures encoded by several multilocus gene families that function synergistically to cause incapacitation. To examine venom evolution, we sequenced and interrog...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2013-12, Vol.110 (51), p.20651-20656
Hauptverfasser:	Vonk, Freek J., Casewell, Nicholas R., Henkel, Christiaan V., Heimberg, Alysha M., Jansen, Hans J., McCleary, Ryan J. R., Kerkkamp, Harald M. E., Vos, Rutger A., Guerreiro, Isabel, Calvete, Juan J., Wüster, Wolfgang, Woods, Anthony E., Logan, Jessica M., Harrison, Robert A., Castoe, Todd A., de Koning, A. P. Jason, Pollock, David D., Yandell, Mark, Calderon, Diego, Renjifo, Camila, Currier, Rachel B., Salgado, David, Pla, Davinia, Sanz, Libia, Hyder, Asad S., Ribeiro, José M. C., Arntzen, Jan W., van den Thillart, Guido E. E. J. M., Boetzer, Marten, Pirovano, Walter, Dirks, Ron P., Spaink, Herman P., Duboule, Denis, McGlinn, Edwina, Kini, Manjunatha, Richardson, Michael K.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptation, Biological - physiology Amniota Animal glands Animals Biological Sciences Correlation analysis data collection Elapid Venoms - genetics Elapid Venoms - metabolism Elapidae - genetics Elapidae - metabolism Evolution Evolution, Molecular Exocrine Glands - metabolism gene duplication Gene expression Genes Genome - physiology Genomes homeotic genes lectins MicroRNA MicroRNAs - genetics MicroRNAs - metabolism natural selection Ophiophagus hannah Platypus Predation predators Proteins proteome Snake venoms Snakes Toxins transcriptome Transcriptome - physiology Transcriptomes Venoms
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