Structure-activity relationships for biodistribution, pharmacokinetics, and excretion of atomically precise nanoclusters in a murine model

The absorption, distribution, metabolism and excretion (ADME) and pharmacokinetic (PK) properties of inorganic nanoparticles with hydrodynamic diameters between 2 and 20 nm are presently unpredictable. It is unclear whether unpredictable in vivo properties and effects arise from a subset of molecule...

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Veröffentlicht in:	Nanoscale 2013-11, Vol.5 (21), p.10525
Hauptverfasser:	Wong, O Andrea, Hansen, Ryan J, Ni, Thomas W, Heinecke, Christine L, Compel, W Scott, Gustafson, Daniel L, Ackerson, Christopher J
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Gold - chemistry Mice Models, Animal Nanoparticles - chemistry Nanoparticles - metabolism Structure-Activity Relationship Surface Properties Tissue Distribution
Online-Zugang:	Volltext
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