Chemical reporters for biological discovery

Bioorthogonal chemistry, facilitated by enzymatic incorporation of chemical reporters in vitro or in cells, permits selective labeling and visualization of proteins, nucleic acids and other biomolecules such as glycans and lipids and facilitates the interrogation of their cellular functions. Functio...

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Veröffentlicht in:	Nature chemical biology 2013-08, Vol.9 (8), p.475-484
Hauptverfasser:	Grammel, Markus, Hang, Howard C
Format:	Artikel
Sprache:	eng
Schlagworte:	631/553 631/92 631/92/458 631/92/96 Alkenes - chemistry Alkynes - chemistry Animals Azides - chemistry Biochemical Engineering Biochemistry Bioorganic Chemistry Cell Biology Chemistry Chemistry/Food Science Genomics Humans Lipids Lipids - chemistry Metabolites Molecular Structure Nucleic acids Nucleic Acids - chemistry Polysaccharides - chemistry Protein synthesis Proteins - chemistry review-article RNA-protein interactions
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