A multi-antigen vaccine targeting neu, IGFBP-2 and IGF-IR prevents tumor progression in mice with pre-invasive breast disease

A multi-antigen multi-peptide vaccine, targeting proteins expressed in pre-invasive breast lesions, can stimulate Type I CD4 + T-cells which have been shown to be deficient in both breast cancer patients and mice that develop mammary tumors. Transgenic mice (TgMMTV-neu) were immunized with a multi-a...

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Veröffentlicht in:	Cancer prevention research (Philadelphia, Pa.) Pa.), 2013-10, Vol.6 (12)
Hauptverfasser:	Disis, Mary L., Gad, Ekram, Herendeen, Daniel R., Lai, Vy P., Park, Kyong Hwa, Cecil, Denise L., O’Meara, Megan M., Treuting, Piper M., Lubet, Ronald A.
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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