Mixture models for single-cell assays with applications to vaccine studies

Blood and tissue are composed of many functionally distinct cell subsets. In immunological studies, these can be measured accurately only using single-cell assays. The characterization of these small cell subsets is crucial to decipher system-level biological changes. For this reason, an increasing...

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Veröffentlicht in:Biostatistics (Oxford, England) England), 2014-01, Vol.15 (1), p.87-101
Hauptverfasser: Finak, Greg, McDavid, Andrew, Chattopadhyay, Pratip, Dominguez, Maria, De Rosa, Steve, Roederer, Mario, Gottardo, Raphael
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Sprache:eng
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